This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
CEACAM6 (human) monoclonal antibody (9A6)
catalog :
ALX-805-083-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
9A6

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry
citations: 10
Reference
Schmitter T, Agerer F, Peterson L, Munzner P, Hauck C. Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens. J Exp Med. 2004;199:35-46 pubmed
Singer B, Scheffrahn I, Heymann R, Sigmundsson K, Kammerer R, Obrink B. Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocyt. J Immunol. 2002;168:5139-46 pubmed
Muenzner P, Billker O, Meyer T, Naumann M. Nuclear factor-kappa B directs carcinoembryonic antigen-related cellular adhesion molecule 1 receptor expression in Neisseria gonorrhoeae-infected epithelial cells. J Biol Chem. 2002;277:7438-46 pubmed
Watt S, Teixeira A, Zhou G, Doyonnas R, Zhang Y, Grunert F, et al. Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site. Blood. 2001;98:1469-79 pubmed
Muenzner P, Naumann M, Meyer T, Gray Owen S. Pathogenic Neisseria trigger expression of their carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1; previously CD66a) receptor on primary endothelial cells by activating the immediate early response transcription factor, nuclear . J Biol Chem. 2001;276:24331-40 pubmed
Muenzner P, Dehio C, Fujiwara T, Achtman M, Meyer T, Gray Owen S. Carcinoembryonic antigen family receptor specificity of Neisseria meningitidis Opa variants influences adherence to and invasion of proinflammatory cytokine-activated endothelial cells. Infect Immun. 2000;68:3601-7 pubmed
Schölzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J. Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol. 2000;156:595-605 pubmed
Krop Watorek A, Laskowska A, Salwa J, Kłopocki A, Grunert F, Ugorski M. CEA-related proteins on human urothelial cell lines of different transformation grades. Cancer Lett. 1999;139:15-22 pubmed
Wang J, Gray Owen S, Knorre A, Meyer T, Dehio C. Opa binding to cellular CD66 receptors mediates the transcellular traversal of Neisseria gonorrhoeae across polarized T84 epithelial cell monolayers. Mol Microbiol. 1998;30:657-71 pubmed
Hanenberg H, Baumann M, Quentin I, Nagel G, Grosse Wilde H, Von Kleist S, et al. Expression of the CEA gene family members NCA-50/90 and NCA-160 (CD66) in childhood acute lymphoblastic leukemias (ALLs) and in cell lines of B-cell origin. Leukemia. 1994;8:2127-33 pubmed
product information
Product ID :
ALX-805-083
Catalog Number :
ALX-805-083-C100
Product Name :
CEACAM6 (human) monoclonal antibody (9A6)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
14707113, 11994468, 11751883, 11520797, 11306560, 10816518, 10666389, 10408904, 9822830, 7808000
Clone :
9A6
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
The normal cross-reacting antigen (NCA) or CEACAM6 belongs to the carcinoembryonic antigen (CEA) gene family. CEACAM6 is a GPI-anchored membrane protein with a single N domain, which shows structural homology to the immunoglobulin variable domains, followed by two immunoglobulin constant-like domains.
ALTnames :
CD66c, NCA
Immunogen :
Tumor cell lines expressing human CEACAM6.
Buffer :
Liquid. In PBS, pH 7.2. Contains no preservatives.
Application Summary :
ELISA, FC, IHC (FS), WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.