This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
CD66e (human) monoclonal antibody (26/3/13)
catalog :
ALX-805-077-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
26/3/13

The same clone is also sold as:
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, flow cytometry
citations: 5
Reference
Schölzel S, Zimmermann W, Schwarzkopf G, Grunert F, Rogaczewski B, Thompson J. Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. Am J Pathol. 2000;156:595-605 pubmed
Krop Watorek A, Laskowska A, Salwa J, Kłopocki A, Grunert F, Ugorski M. CEA-related proteins on human urothelial cell lines of different transformation grades. Cancer Lett. 1999;139:15-22 pubmed
Thompson J, Mössinger S, Reichardt V, Engels U, Beauchemin N, Kommoss F, et al. A polymerase-chain-reaction assay for the specific identification of transcripts encoded by individual carcinoembryonic antigen (CEA)-gene-family members. Int J Cancer. 1993;55:311-9 pubmed
Grunert F, Abuharfeil N, Schwarz K, Von Kleist S. Two CEA and three NCA species, although distinguishable by monoclonal antibodies, have nearly identical peptide patterns. Int J Cancer. 1985;36:357-62 pubmed
Strobel E, Strobel H, Bross K, Winterhalter B, Fiebig H, Schildge J, et al. Effects of human bone marrow stroma on the growth of human tumor cells. Cancer Res. 1989;49:1001-7 pubmed
product information
Product ID :
ALX-805-077
Catalog Number :
ALX-805-077-C100
Product Name :
CD66e (human) monoclonal antibody (26/3/13)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
10666389, 10408904, 7690349, 3839768, 2912545
Clone :
26/3/13
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
CD66e (CEACAM5; CEA) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein with a Mr of 180'000-200'000 which is most strongly expressed on epithelial cells of the fetal and adult colon and to a minor extent on epithelial cells of the stomach and sweat glands, squamous epithelial cells of the tongue, esophagus and cervix. CD66e is used as a tumor marker for early detection of recurrent disease due to its expression in adenocarcinomas of the colon, lung, breast, stomach and pancreas and in mucinous ovarian carcinomas. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
ALTnames :
CEACAM5, CEA, Carcinoembryonic antigen
Immunogen :
CD66e (CEACAM5; CEA) partially purified from a perchloric acid extract from liver metastases of colonic tumors.
Buffer :
Liquid. In PBS, pH 7.2, containing 0.01% sodium azide.
Application Summary :
ELISA, FC, IHC (FS), WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.