Fas (human) monoclonal antibody (APO-1-3) | Enzo Life Sciences ALX-805-020-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Fas (human) monoclonal antibody (APO-1-3)

catalog :

ALX-805-020-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

APO-1-3

The same clone is also sold as:

Abnova: MAB16117

reactivity :

human

application :

western blot, immunoprecipitation, flow cytometry

more info or order :

Enzo Life Sciences product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 2f	Marozin S, Altomonte J, MuÃ±oz Ãlvarez K, Rizzani A, De Toni E, Thasler W, et al. STAT3 inhibition reduces toxicity of oncolytic VSV and provides a potentially synergistic combination therapy for hepatocellular carcinoma. Cancer Gene Ther. 2015;22:317-25 pubmed publisher
	Durrieu L, Dieng M, Le Deist F, Haddad E. Cord blood-derived and peripheral blood-derived cytokine-induced killer cells are sensitive to Fas-mediated apoptosis. Biol Blood Marrow Transplant. 2013;19:1407-11 pubmed publisher
	Kuehn H, Niemela J, Rangel Santos A, Zhang M, Pittaluga S, Stoddard J, et al. Loss-of-function of the protein kinase C ? (PKC?) causes a B-cell lymphoproliferative syndrome in humans. Blood. 2013;121:3117-25 pubmed publisher
	Lo B, Ramaswamy M, Davis J, Price S, Rao V, Siegel R, et al. A rapid ex vivo clinical diagnostic assay for fas receptor-induced T lymphocyte apoptosis. J Clin Immunol. 2013;33:479-88 pubmed publisher
	Kuehn H, Caminha I, Niemela J, Rao V, Davis J, Fleisher T, et al. FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome. J Immunol. 2011;186:6035-43 pubmed publisher
	Ramaswamy M, Cruz A, Cleland S, Deng M, Price S, Rao V, et al. Specific elimination of effector memory CD4+ T cells due to enhanced Fas signaling complex formation and association with lipid raft microdomains. Cell Death Differ. 2011;18:712-20 pubmed publisher
	Chu P, Deforce D, Pedersen I, Kim Y, Kitada S, Reed J, et al. Latent sensitivity to Fas-mediated apoptosis after CD40 ligation may explain activity of CD154 gene therapy in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2002;99:3854-9 pubmed
	Osborne B. Apoptosis and the maintenance of homoeostasis in the immune system. Curr Opin Immunol. 1996;8:245-54 pubmed
	Friesen C, Herr I, Krammer P, Debatin K. Involvement of the CD95 (APO-1/FAS) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med. 1996;2:574-7 pubmed
	Kischkel F, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer P, et al. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 1995;14:5579-88 pubmed
	Debatin K, Goldman C, Waldmann T, Krammer P. APO-1-induced apoptosis of leukemia cells from patients with adult T-cell leukemia. Blood. 1993;81:2972-7 pubmed
	Schattner E, Elkon K, Yoo D, Tumang J, Krammer P, Crow M, et al. CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway. J Exp Med. 1995;182:1557-65 pubmed
	Westendorp M, Frank R, Ochsenbauer C, Stricker K, Dhein J, Walczak H, et al. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature. 1995;375:497-500 pubmed
	Debatin K, Krammer P. Resistance to APO-1 (CD95) induced apoptosis in T-ALL is determined by a BCL-2 independent anti-apoptotic program. Leukemia. 1995;9:815-20 pubmed
	Copeland K, Haaksma A, Goudsmit J, Krammer P, Heeney J. Inhibition of apoptosis in T cells expressing human T cell leukemia virus type I Tax. AIDS Res Hum Retroviruses. 1994;10:1259-68 pubmed

product information

Product ID :

ALX-805-020

Catalog Number :

ALX-805-020-C100

Product Name :

Fas (human) monoclonal antibody (APO-1-3)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

25930184, 11891278, 8725948, 8616718, 8521815, 7684622, 7595225, 7539892, 7539514, 7531462

Clone :

APO-1-3

Isotype :

IgG3

SPECIES REACTIVITY :

Human

ALTnames :

CD95, APO-1, TNFRSF 6

Immunogen :

Human recombinant Fas (CD95; APO-1).

Buffer :

Liquid. In PBS. Contains no preservatives.

Uses :

Functional Application: induces apoptosis with or without cross-linking (Protein A), depending on cell type.

Application Summary :

FC, IP, WB, FUNC

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage