RIG-I (mouse) monoclonal antibody (SS1A) | Enzo Life Sciences ALX-804-960-0100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

RIG-I (mouse) monoclonal antibody (SS1A)

catalog :

ALX-804-960-0100

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

SS1A

application :

western blot

citations: 1

Reference
Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, et al. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med. 2015;21:530-6 pubmed publisher

product information

Product ID :

ALX-804-960

Catalog Number :

ALX-804-960-0100

Product Name :

RIG-I (mouse) monoclonal antibody (SS1A)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

25894825

Clone :

SS1A

Isotype :

IgG2a

SPECIES REACTIVITY :

Mouse

Background :

RIG-1/DDX58 (Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58) is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kDa. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 and MDA5 (melanoma differentiation-associated gene 5) are key intracellular receptors that sense intracellular viral infection and trigger a signal for innate antiviral responses including the production of typeI IFN. Clone SS1A has been shown to be useful for Western blotting of the mouse RIG-1 protein. Involved in innate immune defense against viruses. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses.

ALTnames :

RIG-1, Retinoic acid-inducible gene 1 protein, DEAD-box protein 58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 M, Probable ATP-dependent RNA helicase DDX58

Immunogen :

Synthetic peptide corresponding to C-terminal mouse RIG-I conjugated to KLH.

Buffer :

Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.

Application Summary :

Storage :

+4°C