TRAIL-R1 (human) monoclonal antibody (DJR1) | Enzo Life Sciences ALX-804-912-0100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

TRAIL-R1 (human) monoclonal antibody (DJR1)

catalog :

ALX-804-912-0100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

DJR1

reactivity :

human

application :

western blot, flow cytometry

citations: 1

Reference
Difranco K, Johnson Farley N, Bertino J, Elson D, Vega B, Belinka B, et al. LFA-1-targeting Leukotoxin (LtxA; LeukotheraÂ®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. Leuk Res. 2015;39:649-56 pubmed publisher

product information

Product ID :

ALX-804-912

Catalog Number :

ALX-804-912-0100

Product Name :

TRAIL-R1 (human) monoclonal antibody (DJR1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

Clone :

DJR1

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Background :

DR4 is 56kDa member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-κB, induces apoptosis in the TRAIL ligated cell.

ALTnames :

TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A

Immunogen :

Recombinant human TRAIL-R1 extracellular domain IgG1 Fc fusion protein.

Buffer :

Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.

Application Summary :

FC, WB

Storage :

+4°C