This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
TGF-βRIII (human) monoclonal antibody (Jack-1)
catalog :
ALX-804-871-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Jack-1
application :
western blot, immunoprecipitation
product information
Product ID :
ALX-804-871
Catalog Number :
ALX-804-871-C100
Product Name :
TGF-βRIII (human) monoclonal antibody (Jack-1)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
Clone :
Jack-1
Isotype :
IgG2b
SPECIES REACTIVITY :
Human
Background :
TGF-β receptor III (TGF-βRIII; betaglycan) is an ubiquitously expressed transmembrane proteoglycan TGF-β co-receptor that regulates TGF-β signalling by increasing the binding of TGF-β to the subunit II or TGF-β receptor. (Note: The TGF-β receptor III is a co-receptor of TGF-β receptor, composed of subunit I and II; TGF-β receptor III increases the binding of TGF-β to the subunit II. In this way it can regulate the signaling.) TGF-β receptor III expression is lost in many human breast and prostate cancers and correlates with the resistance to the tumor suppressor effects of TGF-β . The overexpression of TGF-β receptor III in breast cancer cells suppresses their tumorigenicity in an animal model.
ALTnames :
TGFR-3, Transforming growth factor β receptor III, Betaglycan
Immunogen :
Recombinant human TGF-βRIII cytoplasmic domain (aa 809-850).
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Application Summary :
IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.