TRAIL-R3 (human) monoclonal antibody (TR3.06) | Enzo Life Sciences ALX-804-667-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

TRAIL-R3 (human) monoclonal antibody (TR3.06)

catalog :

ALX-804-667-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

TR3.06

The same clone is also sold as:

Abnova: MAB16097

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry

citations: 1

Reference
Ganten T, Sykora J, Koschny R, Batke E, Aulmann S, Mansmann U, et al. Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer. J Mol Med (Berl). 2009;87:995-1007 pubmed publisher

product information

Product ID :

ALX-804-667

Catalog Number :

ALX-804-667-C100

Product Name :

TRAIL-R3 (human) monoclonal antibody (TR3.06)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

19680616

Clone :

TR3.06

Isotype :

IgG1

Product Description :

Specially developed for the immunohistochemical detection of TRAIL-R3 in paraffin embedded tissue. Has been shown to detect TRAIL-R3 expressed at endogenous levels in paraffin-embedded tissue in different mammary carcinoma tissues.

SPECIES REACTIVITY :

Human

Background :

TRAIL-R3 has a higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.TRAIL-R3 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.

ALTnames :

TRAIL receptor 3, DcR1, Death Receptor 1, TRID, CD263, TNFRSF 10C, TNF-related apoptosis-inducing ligand receptor 3, Tumor necrosis factor receptor superfamily member 10C

Immunogen :

Recombinant human TRAIL-R3.

Buffer :

Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

Application Summary :

FC, IHC (PS), WB

Storage :

-20°C