Progerin (human) monoclonal antibody (13A4) | Enzo Life Sciences ALX-804-662-R200 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Progerin (human) monoclonal antibody (13A4)

catalog :

ALX-804-662-R200

quantity :

200 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13A4

The same clone is also sold as:

Abcam: ab66587

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Enzo Life Sciences product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1a	Pellegrini C, Columbaro M, Capanni C, D Apice M, Cavallo C, Murdocca M, et al. All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Oncotarget. 2015;6:29914-28 pubmed publisher
immunocytochemistry; human; 1:10; loading ...; fig 5a	Kubben N, Brimacombe K, Donegan M, Li Z, Misteli T. A high-content imaging-based screening pipeline for the systematic identification of anti-progeroid compounds. Methods. 2016;96:46-58 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1m-o	Baek J, Schmidt E, Viceconte N, Strandgren C, Pernold K, Richard T, et al. Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior. Hum Mol Genet. 2015;24:1305-21 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100	Viceconte N, McKenna T, Eriksson M. Low levels of the reverse transactivator fail to induce target transgene expression in vascular smooth muscle cells. PLoS ONE. 2014;9:e104098 pubmed publisher
	Capanni C, Cenni V, Haraguchi T, Squarzoni S, Schüchner S, Ogris E, et al. Lamin A precursor induces barrier-to-autointegration factor nuclear localization. Cell Cycle. 2010;9:2600-10 pubmed publisher
	Pegoraro G, Kubben N, Wickert U, GÃ¶hler H, Hoffmann K, Misteli T. Ageing-related chromatin defects through loss of the NURD complex. Nat Cell Biol. 2009;11:1261-7 pubmed publisher

product information

Product ID :

ALX-804-662

Catalog Number :

ALX-804-662-R200

Product Name :

Progerin (human) monoclonal antibody (13A4)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

200 µl

list of Pubmed id :

20581439, 19734887

Image Legend 4 :

Figure 1: Western blot analysis (10% PAGE) of whole cell lysate of HeLa cells ectopically expressing FLAG-tagged human progerin. The membrane was cut in strips and each strip was incubated separately with the following antibodies: Lane 1: anti-Lamin A/C antibody (N18) (1:2000), Lane 2: anti-FLAG-tag antibody (M2) (1:5000), Lane 3: MAb to Progerin (human) (13A4) (Prod. No. ALX-804-662) (1:5)

Clone :

13A4

Isotype :

IgG1

SPECIES REACTIVITY :

Human

ALTnames :

Δ50 Lamin A

Immunogen :

Synthetic KLH-coupled peptide corresponding to aa 604-611 (G604AQSPQNC611) at the C-terminus of human progerin.

Buffer :

Liquid. Neat cell culture supernatant containing 0.02% sodium azide.

Application Summary :

ICC, IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage