This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Laminin receptor (67kDa) (human) monoclonal antibody (MLuC5)
catalog :
ALX-804-623-C050
quantity :
50 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
MLuC5

The same clone is also sold as:
reactivity :
human
application :
immunohistochemistry, immunocytochemistry, flow cytometry
citations: 10
Reference
Bonig H, Chang K, Nakamoto B, Papayannopoulou T. The p67 laminin receptor identifies human erythroid progenitor and precursor cells and is functionally important for their bone marrow lodgment. Blood. 2006;108:1230-3 pubmed
Kim K, Chung J, Kim K. 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. J Biol Chem. 2005;280:1360-8 pubmed
Diggle C, Cruickshank S, Olsburgh J, Pellegrin S, Smith B, Banks R, et al. Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor. Am J Pathol. 2003;163:493-504 pubmed
Shmakov A, Bode J, Kilshaw P, Ghosh S. Diverse patterns of expression of the 67-kD laminin receptor in human small intestinal mucosa: potential binding sites for prion proteins?. J Pathol. 2000;191:318-22 pubmed
Canfield S, Khakoo A. The nonintegrin laminin binding protein (p67 LBP) is expressed on a subset of activated human T lymphocytes and, together with the integrin very late activation antigen-6, mediates avid cellular adherence to laminin. J Immunol. 1999;163:3430-40 pubmed
Kitayama J, Nagawa H, Tsuno N, Osada T, Hatano K, Sunami E, et al. Laminin mediates tethering and spreading of colon cancer cells in physiological shear flow. Br J Cancer. 1999;80:1927-34 pubmed
Nadji M, Nassiri M, Fresno M, Terzian E, Morales A. Laminin receptor in lymph node negative breast carcinoma. Cancer. 1999;85:432-6 pubmed
Basolo F, Pollina L, Pacini F, Fontanini G, Menard S, Castronovo V, et al. Expression of the Mr 67,000 laminin receptor is an adverse prognostic indicator in human thyroid cancer: an immunohistochemical study. Clin Cancer Res. 1996;2:1777-80 pubmed
Fontanini G, Vignati S, Chine S, Lucchi M, Mussi A, Angeletti C, et al. 67-Kilodalton laminin receptor expression correlates with worse prognostic indicators in non-small cell lung carcinomas. Clin Cancer Res. 1997;3:227-31 pubmed
de Manzoni G, Guglielmi A, Verlato G, Tomezzoli A, Pelosi G, Schiavon I, et al. Prognostic significance of 67-kDa laminin receptor expression in advanced gastric cancer. Oncology. 1998;55:456-60 pubmed
product information
Product ID :
ALX-804-623
Catalog Number :
ALX-804-623-C050
Product Name :
Laminin receptor (67kDa) (human) monoclonal antibody (MLuC5)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
50 µg
list of Pubmed id :
16609068, 15516338, 12875970, 10878555, 10477615, 10471041, 10023712, 9816129, 9815677, 9732225
Clone :
MLuC5
Isotype :
IgM
SPECIES REACTIVITY :
Human
Background :
The interactions between tumor cells and laminin or other components of the extracellular matrix have been shown to play an important role in tumor invasion and metastasis. They are mediated by different cell surface molecules such as the 67kD laminin receptor (67LR; laminin receptor 1), a protein derived from a smaller precursor, the 37LRP. In addition to its role as laminin receptor, 67LR also acts as a receptor for viruses and is involved with internalization of the prion protein.
ALTnames :
67-kDa laminin receptor, 67LR, Laminin receptor 1, Colon carcinoma laminin-binding protein, 40S ribosomal protein SA, p40, 37LRP, RPSA
Immunogen :
Extracellular part of recombinant human of 67kDa laminin receptor (laminin receptor 1; 67LR) (monomeric).
Specificity :
Recognizes the extracellular part of the 67kDa laminin receptor.
Buffer :
Liquid. In 20mM TRIS, pH 7.4, containing 150mM sodium chloride and 0.02% sodium azide.
Uses :
Functional Application: Partially inhibits the binding of soluble laminin.
Application Summary :
FC, ICC, IHC (FS), IHC (PS), FUNC
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.