SEL1L monoclonal antibody (MSel1) | Enzo Life Sciences ALX-804-579-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

SEL1L monoclonal antibody (MSel1)

catalog :

ALX-804-579-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MSel1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 6

Reference
Schelhaas M, Malmstrom J, Pelkmans L, Haugstetter J, Ellgaard L, Grünewald K, et al. Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells. Cell. 2007;131:516-29 pubmed
Kaneko M, Yasui S, Niinuma Y, Arai K, Omura T, Okuma Y, et al. A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes. FEBS Lett. 2007;581:5355-60 pubmed
Biunno I, Cattaneo M, Orlandi R, Canton C, Biagiotti L, Ferrero S, et al. SEL1L a multifaceted protein playing a role in tumor progression. J Cell Physiol. 2006;208:23-38 pubmed
Cattaneo M, Orlandini S, Beghelli S, Moore P, Sorio C, Bonora A, et al. SEL1L expression in pancreatic adenocarcinoma parallels SMAD4 expression and delays tumor growth in vitro and in vivo. Oncogene. 2003;22:6359-68 pubmed
Orlandi R, Cattaneo M, Troglio F, Campiglio M, Biunno I, Menard S. Production of a monoclonal antibody directed against the recombinant SEL1L protein. Int J Biol Markers. 2002;17:104-11 pubmed
Orlandi R, Cattaneo M, Troglio F, Casalini P, Ronchini C, Menard S, et al. SEL1L expression decreases breast tumor cell aggressiveness in vivo and in vitro. Cancer Res. 2002;62:567-74 pubmed

product information

Product ID :

ALX-804-579

Catalog Number :

ALX-804-579-C100

Product Name :

SEL1L monoclonal antibody (MSel1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

17981119, 17967421, 16331677, 14508516, 12113576, 11809711

Clone :

MSel1

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse

Background :

SEL1L (suppressor of lin-12-like protein) is the human ortholog of the C. elegans sel-1 gene, a negative regulator of the lin-12/Notch family of proteins. Human SEL1L is a component of endoplasmic reticulum-associated degradation (ERAD), involved in ubiquitin-dependent degradation of misfolded ER proteins. In addition, SEL1L plays a role in cancer progression. Several studies provided significant evidence that increased SEL1L expression is linked to a decrease in tumor aggressiveness.

ALTnames :

Suppressor of lin-12-like protein

Immunogen :

Recombinant human SEL1L (suppressor of lin-12-like protein).

Buffer :

Liquid. In 150mM sodium chloride, pH 7.4, containing 0.02% sodium azide.

Application Summary :

IHC (FS), IHC (PS), IP, WB

Storage :

+4°C