BimS/EL/L monoclonal antibody (10B12) | Enzo Life Sciences ALX-804-528-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

BimS/EL/L monoclonal antibody (10B12)

catalog :

ALX-804-528-C100

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

10B12

reactivity :

human, mouse, rat, dogs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

Enzo Life Sciences product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse western blot; mouse	Bai L, Chen J, McEachern D, Liu L, Zhou H, Aguilar A, et al. BM-1197: a novel and specific Bcl-2/Bcl-xL inhibitor inducing complete and long-lasting tumor regression in vivo. PLoS ONE. 2014;9:e99404 pubmed publisher
	O Reilly L, Kruse E, Puthalakath H, Kelly P, Kaufmann T, Huang D, et al. MEK/ERK-mediated phosphorylation of Bim is required to ensure survival of T and B lymphocytes during mitogenic stimulation. J Immunol. 2009;183:261-9 pubmed publisher
	Labi V, Erlacher M, Kiessling S, Manzl C, Frenzel A, O Reilly L, et al. Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med. 2008;205:641-55 pubmed publisher
	Liston A, Lesage S, Gray D, O Reilly L, Strasser A, Fahrer A, et al. Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity. 2004;21:817-30 pubmed

product information

Product ID :

ALX-804-528

Catalog Number :

ALX-804-528-C100

Product Name :

BimS/EL/L monoclonal antibody (10B12)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

19542438, 18299399, 15589170

Clone :

10B12

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Rat, Monkey, Dog

ALTnames :

BCL2L11

Immunogen :

Synthetic peptide corresponding to aa 20-40 (Q20PAERPPQLRPGAPTSLQTEP40) of mouse BimL.

Specificity :

Recognizes an epitope within aa 20-40 of BimL, BimEL, and BimS. Also recognizes the six novel isoforms of human Bim, generated by alternative splicing and lacking the C-terminal hydrophobic region recently identified.

Buffer :

Liquid. Protein G affinity purified antibody in PBS containing 25% glycerol and 0.02% sodium azide.

Application Summary :

ELISA, FC, ICC, IHC, IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage