This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
IL-13 receptor (human) monoclonal antibody (GM-1C8)
catalog :
ALX-804-506-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
GM-1C8
reactivity :
human
application :
flow cytometry
citations: 1
Reference
Krause S, Behrends J, Borowski A, Lohrmann J, Lang S, Myrtek D, et al. Blockade of interleukin-13-mediated cell activation by a novel inhibitory antibody to human IL-13 receptor alpha1. Mol Immunol. 2006;43:1799-807 pubmed
product information
Product ID :
ALX-804-506
Catalog Number :
ALX-804-506-C100
Product Name :
IL-13 receptor (human) monoclonal antibody (GM-1C8)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
16364441
Clone :
GM-1C8
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
IL-13 is an immunoregulatory cytokine secreted predominantly by activated TH2 cells, as well as mast cells and basophils, and is a key mediator in the pathogenesis of allergic inflammation. The human IL-13 receptor (IL-13R) is a heterodimer composed of the interleukin-4 receptor a chain (IL-4Rα) and an IL-13 binding protein, IL-13Rα1.A second IL-13 binding protein, IL-13Rα2, has also been identified, which is believed to act as a "decoy" receptor. IL-13 receptors are expressed on human B cells, basophils, eosinophils, mast cells, endothelial cells, fibroblasts, monocytes, macrophages, respiratory epithelial cells, and smooth muscle cells. However, functional IL-13 receptors have not been demonstrated on human or mouse T cells. As with other cytokine receptors, the cytoplasmic tails of IL-4 and IL-13 receptor subunits associate with tyrosine kinases of the Janus family (JAK 1
ALTnames :
IL-13R, CD213, Interleukin-13 receptor
Immunogen :
Vector containing the cDNA of the extracellular domain of human IL-13Rα1 (interleukin-13 receptor α1 chain).
Buffer :
Liquid. Antibody in PBS, pH 7.2, containing 0.01% sodium azide.
Application Summary :
FC
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.