product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
PTX3 monoclonal antibody (MNB4)
catalog :
ALX-804-464-C100
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MNB4
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 3a-c
  • ELISA; human; 1:2000; loading ...; fig 1a, b
Pang Y, Tan Y, Li Y, Zhang J, Guo Y, Guo Z, et al. Pentraxin 3 Is Closely Associated With Tubulointerstitial Injury in Lupus Nephritis: A Large Multicenter Cross-Sectional Study. Medicine (Baltimore). 2016;95:e2520 pubmed publisher
  • immunohistochemistry; rat; 1:50; loading ...; fig 8c
Baetta R, Lento S, Ghilardi S, Barbati E, Corsini A, Tremoli E, et al. Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation. Vascul Pharmacol. 2015;67-69:38-47 pubmed publisher
  • immunohistochemistry; human; 1:200
  • ELISA; human; 1:1000
  • western blot; human
Zhang S, Zhu Y, Chen S, He H, Tseng S. Constitutive expression of pentraxin 3 (PTX3) protein by human amniotic membrane cells leads to formation of the heavy chain (HC)-hyaluronan (HA)-PTX3 complex. J Biol Chem. 2014;289:13531-42 pubmed publisher
Barbui T, Carobbio A, Finazzi G, Vannucchi A, Barosi G, Antonioli E, et al. Inflammation and thrombosis in essential thrombocythemia and polycythemia vera: different role of C-reactive protein and pentraxin 3. Haematologica. 2011;96:315-8 pubmed publisher
Jaillon S, Jeannin P, Hamon Y, Fremaux I, Doni A, Bottazzi B, et al. Endogenous PTX3 translocates at the membrane of late apoptotic human neutrophils and is involved in their engulfment by macrophages. Cell Death Differ. 2009;16:465-74 pubmed publisher
Boehme M, Kaehne F, Kuehne A, Bernhardt W, Schröder M, Pommer W, et al. Pentraxin 3 is elevated in haemodialysis patients and is associated with cardiovascular disease. Nephrol Dial Transplant. 2007;22:2224-9 pubmed
Jaillon S, Peri G, Delneste Y, Fremaux I, Doni A, Moalli F, et al. The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J Exp Med. 2007;204:793-804 pubmed
Bussolati B, Peri G, Salvidio G, Verzola D, Mantovani A, Camussi G. The long pentraxin PTX3 is synthesized in IgA glomerulonephritis and activates mesangial cells. J Immunol. 2003;170:1466-72 pubmed
Rolph M, Zimmer S, Bottazzi B, Garlanda C, Mantovani A, Hansson G. Production of the long pentraxin PTX3 in advanced atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 2002;22:e10-4 pubmed
Peri G, Introna M, Corradi D, Iacuitti G, Signorini S, Avanzini F, et al. PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans. Circulation. 2000;102:636-41 pubmed
Bottazzi B, Vouret Craviari V, Bastone A, De Gioia L, Matteucci C, Peri G, et al. Multimer formation and ligand recognition by the long pentraxin PTX3. Similarities and differences with the short pentraxins C-reactive protein and serum amyloid P component. J Biol Chem. 1997;272:32817-23 pubmed
product information
Product ID :
ALX-804-464
Catalog Number :
ALX-804-464-C100
Product Name :
PTX3 monoclonal antibody (MNB4)
Host species :
Rat
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
25849951, 21173097, 19079137, 17496115, 17389238, 12538709, 12006411, 10931803, 9407058
Clone :
MNB4
Isotype :
IgG2a
SPECIES REACTIVITY :
Human, Rat
ALTnames :
Pentraxin 3, TSG-14, TNF stimulated gene-14
Immunogen :
Recombinant human PTX3 (pentraxin 3).
Specificity :
Recognizes the N-terminus of PTX3.
Buffer :
Liquid. In PBS containing 0.1% sodium azide.
Uses :
Excellent for ELISA (capture).
Application Summary :
ELISA, FC, IHC (FS), IP, WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.