product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Caspase-8 (mouse) monoclonal antibody (3B10)
catalog :
ALX-804-448-C100
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
3B10
reactivity :
mouse
application :
western blot, ELISA, immunocytochemistry, flow cytometry, western blot knockout validation
more info or order :
Enzo Life Sciences product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 1 ug/ml; loading ...; fig 8a
Antonopoulos C, Russo H, El Sanadi C, Martin B, Li X, Kaiser W, et al. Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling. J Biol Chem. 2015;290:20167-84 pubmed publisher
O Reilly L, Tai L, Lee L, Kruse E, Grabow S, Fairlie W, et al. Membrane-bound Fas ligand only is essential for Fas-induced apoptosis. Nature. 2009;461:659-63 pubmed publisher
Kovalenko A, Kim J, Kang T, Rajput A, Bogdanov K, Dittrich Breiholz O, et al. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med. 2009;206:2161-77 pubmed publisher
Shackleton M, O Reilly L, Sutherland K, Bath M, Ellis S, Strasser A, et al. Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium. Dev Dyn. 2009;238:1010-6 pubmed publisher
Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, et al. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J Exp Med. 2008;205:1967-73 pubmed publisher
O Reilly L, Divisekera U, Newton K, Scalzo K, Kataoka T, Puthalakath H, et al. Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes. Cell Death Differ. 2004;11:724-36 pubmed
product information
Product ID :
ALX-804-448
Catalog Number :
ALX-804-448-C100
Product Name :
Caspase-8 (mouse) monoclonal antibody (3B10)
Host species :
Rat
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
19794494, 19720838, 19301394, 18725521, 15017386
Clone :
3B10
Isotype :
IgG1
SPECIES REACTIVITY :
Mouse
ALTnames :
FLICE
Immunogen :
Recombinant mouse caspase-8 p18 subunit.
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Uses :
ELISA: recombinant mouse caspase-8. Flow Cytometry: overexpressed casepase-8. Excellent for Immunocytochemistry. Detects bands of ~55kDa (full-length caspase-8) and ~18kDa (apoptosis-induced cleavage fragment) by Western blot.
Application Summary :
ELISA, FC, ICC, WB
Storage :
-20°C
more info or order :
Enzo Life Sciences product webpage
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.