Folate receptor α monoclonal antibody (Mov18) | Enzo Life Sciences ALX-804-439-R100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Folate receptor α monoclonal antibody (Mov18)

catalog :

ALX-804-439-R100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MOv18

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 14

Reference
Schutsky K, Song D, Lynn R, Smith J, Poussin M, Figini M, et al. Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor. Oncotarget. 2015;6:28911-28 pubmed publisher
Hansen M, Greibe E, Skovbjerg S, Rohde S, Kristensen A, Jensen T, et al. Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha. Cell Signal. 2015;27:1356-68 pubmed publisher
Mornet E, Carmoy N, Lainé C, Lemiègre L, Le Gall T, Laurent I, et al. Folate-equipped nanolipoplexes mediated efficient gene transfer into human epithelial cells. Int J Mol Sci. 2013;14:1477-501 pubmed publisher
Urbanska K, Lanitis E, Poussin M, Lynn R, Gavin B, Kelderman S, et al. A universal strategy for adoptive immunotherapy of cancer through use of a novel T-cell antigen receptor. Cancer Res. 2012;72:1844-52 pubmed publisher
Song D, Ye Q, Poussin M, Harms G, Figini M, Powell D. CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo. Blood. 2012;119:696-706 pubmed publisher
Solanky N, Requena Jimenez A, D Souza S, Sibley C, Glazier J. Expression of folate transporters in human placenta and implications for homocysteine metabolism. Placenta. 2010;31:134-43 pubmed publisher
Steinfeld R, Grapp M, Kraetzner R, Dreha Kulaczewski S, Helms G, Dechent P, et al. Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism. Am J Hum Genet. 2009;85:354-63 pubmed publisher
Basal E, Eghbali Fatourechi G, Kalli K, Hartmann L, Goodman K, Goode E, et al. Functional folate receptor alpha is elevated in the blood of ovarian cancer patients. PLoS ONE. 2009;4:e6292 pubmed publisher
Rosenholm J, Meinander A, Peuhu E, Niemi R, Eriksson J, Sahlgren C, et al. Targeting of porous hybrid silica nanoparticles to cancer cells. ACS Nano. 2009;3:197-206 pubmed publisher
Carr T, Adair S, Fink M, Hogan K. Immunological profiling of a panel of human ovarian cancer cell lines. Cancer Immunol Immunother. 2008;57:31-42 pubmed
Tomassetti A, Bottero F, Mazzi M, Miotti S, Colnaghi M, Canevari S. Molecular requirements for attachment of the glycosylphosphatidylinositol anchor to the human alpha folate receptor. J Cell Biochem. 1999;72:111-8 pubmed
Corona G, Giannini F, Fabris M, Toffoli G, Boiocchi M. Role of folate receptor and reduced folate carrier in the transport of 5-methyltetrahydrofolic acid in human ovarian carcinoma cells. Int J Cancer. 1998;75:125-33 pubmed
Tomassetti A, Coney L, Canevari S, Miotti S, Facheris P, Zurawski V, et al. Isolation and biochemical characterization of the soluble and membrane forms of folate binding protein expressed in the ovarian carcinoma cell line IGROV1. FEBS Lett. 1993;317:143-6 pubmed
Gesmundo N, Calonghi N, Sartor G, Farruggia G, Miotti S, Canevari S, et al. Effect of hydrostatic pressure and cholesterol depletion on the expression of a tumor-associated antigen. Eur J Biochem. 1993;217:337-43 pubmed

product information

Product ID :

ALX-804-439

Catalog Number :

ALX-804-439-R100

Product Name :

Folate receptor α monoclonal antibody (Mov18)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

list of Pubmed id :

25841994, 20036773, 19732866, 19617914, 19206267, 17579858, 10025672, 9426700, 8428622, 8223571

Clone :

Mov18

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Monkey

Background :

The folate receptor is a highly selective tumor marker overexpressed in greater than 90% of ovarian carcinomas.

ALTnames :

Folate-binding protein, gp38, FRα, FOLR1

Immunogen :

Membrane preparation from a human ovarian carcinoma specimen.

Specificity :

Recognizes membrane-bound and soluble folate receptor (FR) α.

Buffer :

Liquid. In PBS, pH 7.4. Contains no preservatives.

Uses :

Not recommended for IHC (PS).

Application Summary :

FC, ICC, IHC (FS), IP, WB

Storage :

+4°C