This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Toll-like receptor 4 (human) monoclonal antibody (HTA125) (FITC conjugate)
catalog :
ALX-804-419F-T100
quantity :
100 tests
clonality :
monoclonal
host :
mouse
conjugate :
FITC
reactivity :
human
application :
immunoprecipitation, flow cytometry
citations: 10
Reference
Chessa D, Spiga L, De Riu N, Delaconi P, Mazzarello V, Ganau G, et al. Lipopolysaccharides belonging to different Salmonella serovars are differentially capable of activating Toll-like receptor 4. Infect Immun. 2014;82:4553-62 pubmed publisher
Gaudreault E, Paquet Bouchard C, Fiola S, Le Bel M, Lacerte P, Shio M, et al. TAK1 contributes to the enhanced responsiveness of LTB(4)-treated neutrophils to Toll-like receptor ligands. Int Immunol. 2012;24:693-704 pubmed publisher
Sato K, Yoshimura A, Kaneko T, Ukai T, Ozaki Y, Nakamura H, et al. A single nucleotide polymorphism in 3'-untranslated region contributes to the regulation of Toll-like receptor 4 translation. J Biol Chem. 2012;287:25163-72 pubmed publisher
Nakaira Takahagi E, Golim M, Bannwart C, Puccia R, Peraçoli M. Interactions between TLR2, TLR4, and mannose receptors with gp43 from Paracoccidioides brasiliensis induce cytokine production by human monocytes. Med Mycol. 2011;49:694-703 pubmed publisher
Chochi K, Ichikura T, Kinoshita M, Majima T, Shinomiya N, Tsujimoto H, et al. Helicobacter pylori augments growth of gastric cancers via the lipopolysaccharide-toll-like receptor 4 pathway whereas its lipopolysaccharide attenuates antitumor activities of human mononuclear cells. Clin Cancer Res. 2008;14:2909-17 pubmed publisher
Lasarte J, Casares N, Gorraiz M, Hervas Stubbs S, Arribillaga L, Mansilla C, et al. The extra domain A from fibronectin targets antigens to TLR4-expressing cells and induces cytotoxic T cell responses in vivo. J Immunol. 2007;178:748-56 pubmed
Grabig A, Paclik D, Guzy C, Dankof A, Baumgart D, Erckenbrecht J, et al. Escherichia coli strain Nissle 1917 ameliorates experimental colitis via toll-like receptor 2- and toll-like receptor 4-dependent pathways. Infect Immun. 2006;74:4075-82 pubmed
Falcone S, Perrotta C, De Palma C, Pisconti A, Sciorati C, Capobianco A, et al. Activation of acid sphingomyelinase and its inhibition by the nitric oxide/cyclic guanosine 3',5'-monophosphate pathway: key events in Escherichia coli-elicited apoptosis of dendritic cells. J Immunol. 2004;173:4452-63 pubmed
Latz E, Visintin A, Lien E, Fitzgerald K, Monks B, Kurt Jones E, et al. Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J Biol Chem. 2002;277:47834-43 pubmed
Triantafilou M, Miyake K, Golenbock D, Triantafilou K. Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation. J Cell Sci. 2002;115:2603-11 pubmed
product information
Product ID :
ALX-804-419F
Catalog Number :
ALX-804-419F-T100
Product Name :
Toll-like receptor 4 (human) monoclonal antibody (HTA125) (FITC conjugate)
Host species :
Mouse
Clonality :
Monoclonal
Conjugation :
FITC
Product Type :
Antibody
Size :
100 tests
list of Pubmed id :
25135686, 22843747, 22661708, 21417682, 18483357, 17202335, 16790781, 15383576, 12324469, 12045230
Clone :
HTA125
Isotype :
IgG2a
SPECIES REACTIVITY :
Human
ALTnames :
TLR4, CD284
Immunogen :
Ba/F3 cell line expressing human TLR4 (Toll-like receptor 4).
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Uses :
Not suitable for Western blot (does not detect denatured protein).
Application Summary :
FC, IP
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.