This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Toll-like receptor 8 monoclonal antibody (44C143) (biotin conjugate)
catalog :
ALX-804-376B-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
44C143

The same clone is also sold as:
reactivity :
human, mouse
citations: 2
Reference
Luangsay S, Ait Goughoulte M, Michelet M, Floriot O, Bonnin M, Gruffaz M, et al. Expression and functionality of Toll- and RIG-like receptors in HepaRG cells. J Hepatol. 2015;63:1077-85 pubmed publisher
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production. Surgery. 2006;140:170-8 pubmed
product information
Product ID :
ALX-804-376B
Catalog Number :
ALX-804-376B-C100
Product Name :
Toll-like receptor 8 monoclonal antibody (44C143) (biotin conjugate)
Host species :
Mouse
Clonality :
Monoclonal
Conjugation :
Biotin
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
16904966
Clone :
44C143
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse
Background :
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kDa.
ALTnames :
TLR8, CD288
Immunogen :
Synthetic peptide corresponding to aa 750-850 of the cytoplasmic portion of human TLR8 (Toll-like receptor 8).
Buffer :
Liquid. In PBS containing 0.05% sodium azide.
Uses :
Detects a band of ~120kDa by Western blot.
Application Summary :
ELISA
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.