product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Toll-like receptor 8 monoclonal antibody (44C143)
catalog :
ALX-804-376-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
44C143
reactivity :
human, mouse
application :
western blot, immunohistochemistry, flow cytometry
more info or order :
Enzo Life Sciences product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 2
Luangsay S, Ait Goughoulte M, Michelet M, Floriot O, Bonnin M, Gruffaz M, et al. Expression and functionality of Toll- and RIG-like receptors in HepaRG cells. J Hepatol. 2015;63:1077-85 pubmed publisher
Xu S, Koldovsky U, Xu M, Wang D, Fitzpatrick E, Son G, et al. High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production. Surgery. 2006;140:170-8 pubmed
product information
Product ID :
ALX-804-376
Catalog Number :
ALX-804-376-C100
Product Name :
Toll-like receptor 8 monoclonal antibody (44C143)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
16904966
Clone :
44C143
Isotype :
IgG1
SPECIES REACTIVITY :
Human, Mouse
Background :
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kDa.
ALTnames :
TLR8, CD288
Immunogen :
Synthetic peptide corresponding to aa 750-850 of the cytoplasmic portion of human TLR8 (Toll-like receptor 8).
Buffer :
Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.
Uses :
Detects a band of ~120kDa by Western blot. Flow Cytometry: Suitable for cell surface and intracellular FC.
Application Summary :
FC, IHC (PS), WB
Storage :
-20°C
more info or order :
Enzo Life Sciences product webpage
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.