Caspase-2 monoclonal antibody (10C6) | Enzo Life Sciences ALX-804-355-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Caspase-2 monoclonal antibody (10C6)

catalog :

ALX-804-355-C100

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

10C6

The same clone is also sold as:

Abnova: MAB3484

reactivity :

human, mouse, rat, dogs

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

Enzo Life Sciences product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; fig 1	Lopez Cruzan M, Sharma R, Tiwari M, Karbach S, Holstein D, Martin C, et al. Caspase-2 resides in the mitochondria and mediates apoptosis directly from the mitochondrial compartment. Cell Death Discov. 2016;2: pubmed
western blot; mouse	Sandow J, Dorstyn L, O Reilly L, Tailler M, Kumar S, Strasser A, et al. ER stress does not cause upregulation and activation of caspase-2 to initiate apoptosis. Cell Death Differ. 2014;21:475-80 pubmed publisher
western blot; human	Jelinek M, Balusikova K, Kopperová D, Němcová Fürstová V, Srámek J, Fidlerova J, et al. Caspase-2 is involved in cell death induction by taxanes in breast cancer cells. Cancer Cell Int. 2013;13:42 pubmed publisher
	Marsden V, Kaufmann T, O Reilly L, Adams J, Strasser A. Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death. Blood. 2006;107:1872-7 pubmed
	Scott C, Schuler M, Marsden V, Egle A, Pellegrini M, Nesic D, et al. Apaf-1 and caspase-9 do not act as tumor suppressors in myc-induced lymphomagenesis or mouse embryo fibroblast transformation. J Cell Biol. 2004;164:89-96 pubmed
	O Reilly L, Ekert P, Harvey N, Marsden V, Cullen L, Vaux D, et al. Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ. 2002;9:832-41 pubmed

product information

Product ID :

ALX-804-355

Catalog Number :

ALX-804-355-C100

Product Name :

Caspase-2 monoclonal antibody (10C6)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

16291596, 14709542, 12107826

Clone :

10C6

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Rat, Monkey, Dog

Immunogen :

Recombinant human caspase-2 (p19 subunit).

Specificity :

Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2.

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Application Summary :

ELISA, FC, ICC, IHC (FS)

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage