BimS/EL/L monoclonal antibody (14A8) | Enzo Life Sciences ALX-804-351-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

BimS/EL/L monoclonal antibody (14A8)

catalog :

ALX-804-351-C100

quantity :

100 µg

price :

349 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

14A8

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, western blot knockout validation

more info or order :

Enzo Life Sciences product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; fig 2c	Merino D, Giam M, Hughes P, Siggs O, Heger K, O'Reilly L, et al. The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins. J Cell Biol. 2009;186:355-62 pubmed publisher
	Bouillet P, Purton J, Godfrey D, Zhang L, Coultas L, Puthalakath H, et al. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature. 2002;415:922-6 pubmed
	O'Reilly L, Cullen L, Visvader J, Lindeman G, Print C, Bath M, et al. The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells. Am J Pathol. 2000;157:449-61 pubmed
	Putcha G, Moulder K, Golden J, Bouillet P, Adams J, Strasser A, et al. Induction of BIM, a proapoptotic BH3-only BCL-2 family member, is critical for neuronal apoptosis. Neuron. 2001;29:615-28 pubmed
	Puthalakath H, Huang D, O'Reilly L, King S, Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell. 1999;3:287-96 pubmed
	Zhu Y, Swanson B, Wang M, Hildeman D, Schaefer B, Liu X, et al. Constitutive association of the proapoptotic protein Bim with Bcl-2-related proteins on mitochondria in T cells. Proc Natl Acad Sci U S A. 2004;101:7681-6 pubmed
	O'Reilly L, Cullen L, Moriishi K, O'Connor L, Huang D, Strasser A. Rapid hybridoma screening method for the identification of monoclonal antibodies to low-abundance cytoplasmic proteins. Biotechniques. 1998;25:824-30 pubmed
	Bouillet P, Metcalf D, Huang D, Tarlinton D, Kay T, Kontgen F, et al. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science. 1999;286:1735-8 pubmed

product information

Product ID :

ALX-804-351

Catalog Number :

ALX-804-351-C100

Product Name :

BimS/EL/L monoclonal antibody (14A8)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

List Price (USD) :

349 USD

list of Pubmed id :

19651893, 15136728, 11859372, 11301022, 10934149, 10576740, 10198631, 9821584

Clone :

14A8

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse, Monkey

ALTnames :

BCL2L11

Immunogen :

Recombinant mouse BimS.

Specificity :

Recognizes BimL, BimEL and BimS.

Buffer :

Liquid. In PBS containing 10mM sodium azide.

Application Summary :

FC, ICC, IHC (PS), IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage