Apaf-1 (human) monoclonal antibody (2E12) | Enzo Life Sciences ALX-804-348-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Apaf-1 (human) monoclonal antibody (2E12)

catalog :

ALX-804-348-C100

quantity :

100 µg

price :

317 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

2E12

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4f	Leslie P, Franklin D, Liu Y, Zhang Y. p53 Regulates the Expression of LRP1 and Apoptosis through a Stress Intensity-Dependent MicroRNA Feedback Loop. Cell Rep. 2018;24:1484-1495 pubmed publisher
	Londoño Joshi A, Oliver P, Li Y, Lee C, Forero Torres A, LoBuglio A, et al. Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity. Breast Cancer Res Treat. 2012;133:437-45 pubmed publisher
	Cho D, Hong Y, Lee H, Woo H, Pyo J, Mak T, et al. Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein. J Biol Chem. 2004;279:39942-50 pubmed
	Yakovlev A, Di Giovanni S, Wang G, Liu W, Stoica B, Faden A. BOK and NOXA are essential mediators of p53-dependent apoptosis. J Biol Chem. 2004;279:28367-74 pubmed
	Adachi K, Osaki M, Kase S, Takeda A, Ito H. Anti-Fas antibody-induced apoptosis and its signal transduction in human gastric carcinoma cell lines. Int J Oncol. 2003;23:713-9 pubmed
	Hausmann G, O Reilly L, van Driel R, Beaumont J, Strasser A, Adams J, et al. Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L). J Cell Biol. 2000;149:623-34 pubmed
	Moriishi K, Huang D, Cory S, Adams J. Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1. Proc Natl Acad Sci U S A. 1999;96:9683-8 pubmed

product information

Product ID :

ALX-804-348

Catalog Number :

ALX-804-348-C100

Product Name :

Apaf-1 (human) monoclonal antibody (2E12)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

List Price (USD) :

317 USD

list of Pubmed id :

15262985, 15102863, 12888908, 10791976, 10449754

Clone :

2E12

Isotype :

IgG2a

SPECIES REACTIVITY :

Human

ALTnames :

Apoptosis protease-activating factor 1

Immunogen :

Recombinant human Apaf-1 (apoptosis protease-activating factor 1) N-terminal CARD and CED-4 homologous domains (aa 1-464) .

Specificity :

Recognizes the CARD domain of Apaf-1.

Buffer :

Liquid. In PBS containing 0.02% sodium azide.

Application Summary :

ELISA, ICC, IHC (FS), IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage