product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
TRAIL-R3 (human) monoclonal antibody (HS301)
catalog :
ALX-804-344A-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
HS301
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 7
Published Application/Species/Sample/Dilution | Reference |
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Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, et al. Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression. Blood. 2008;111:4780-7 pubmed publisher
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Koschny R, Ganten T, Sykora J, Haas T, Sprick M, Kolb A, et al. TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window. Hepatology. 2007;45:649-58 pubmed
| |
Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, et al. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes. J Biol Chem. 2004;279:52824-34 pubmed
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Ganten T, Haas T, Sykora J, Stahl H, Sprick M, Fas S, et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ. 2004;11 Suppl 1:S86-96 pubmed
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Secchiero P, Melloni E, Heikinheimo M, Mannisto S, Di Pietro R, Iacone A, et al. TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. Blood. 2004;103:517-22 pubmed
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Washburn B, Weigand M, Grosse Wilde A, Janke M, Stahl H, Rieser E, et al. TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus. J Immunol. 2003;170:1814-21 pubmed
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product information
Product ID :
ALX-804-344A
Catalog Number :
ALX-804-344A-C100
Product Name :
TRAIL-R3 (human) monoclonal antibody (HS301)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
18314443, 17326159, 15459191, 15105837, 12969966, 12574346
Clone :
HS301
Isotype :
IgG1
SPECIES REACTIVITY :
Human
ALTnames :
TRAIL receptor 3, DcR1, Death Receptor 1, TRID, CD263, TNFRSF 10C, TNF-related apoptosis-inducing ligand receptor 3, Tumor necrosis factor receptor superfamily member 10C
Immunogen :
Recombinant human TRAIL-R3.
Buffer :
Liquid. In PBS containing 0.05% sodium azide.
Uses :
For Western blot of whole cell lysate, use PAb to TRAIL-R3 (human) (from goat) (Prod. No. ALX-210-744).
Application Summary :
FC, ICC
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.
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