This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Smac/DIABLO (human) monoclonal antibody (10G7)
catalog :
ALX-804-333-C100
quantity :
100 µg
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
10G7
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 4
Reference
Han J, Goldstein L, Gastman B, Froelich C, Yin X, Rabinowich H. Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events. J Biol Chem. 2004;279:22020-9 pubmed
Tikoo A, O Reilly L, Day C, Verhagen A, Pakusch M, Vaux D. Tissue distribution of Diablo/Smac revealed by monoclonal antibodies. Cell Death Differ. 2002;9:710-6 pubmed
Luetjens C, Kogel D, Reimertz C, Dussmann H, Renz A, Schulze Osthoff K, et al. Multiple kinetics of mitochondrial cytochrome c release in drug-induced apoptosis. Mol Pharmacol. 2001;60:1008-19 pubmed
Kataoka T, Holler N, Micheau O, Martinon F, Tinel A, Hofmann K, et al. Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension. J Biol Chem. 2001;276:19548-54 pubmed
product information
Product ID :
ALX-804-333
Catalog Number :
ALX-804-333-C100
Product Name :
Smac/DIABLO (human) monoclonal antibody (10G7)
Host species :
Rat
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
15014070, 12058276, 11641429, 11262395
Clone :
10G7
Isotype :
IgG2a
SPECIES REACTIVITY :
Human
ALTnames :
Second mitochondria-derived activator of caspase
Immunogen :
Recombinant mouse Smac/DIABLO (aa 55-237).
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Uses :
Detects bands of ~29kDa (full length) and ~23kDa (mature form) by Western blot. For detection of mouse Smac/DIABLO, use MAb to Smac/DIABLO (mouse) (9H10) (Prod. No. ALX-804-366).
Application Summary :
ELISA, FC, ICC, IP, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.