Caspase-3 monoclonal antibody (31A1067) | Enzo Life Sciences ALX-804-305-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Caspase-3 monoclonal antibody (31A1067)

catalog :

ALX-804-305-C100

quantity :

100 µg

price :

307 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

31A1067

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

Enzo Life Sciences product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 2g	Pulito C, Mori F, Sacconi A, Casadei L, Ferraiuolo M, Valerio M, et al. Cynara scolymus affects malignant pleural mesothelioma by promoting apoptosis and restraining invasion. Oncotarget. 2015;6:18134-50 pubmed
western blot; human	Ferro M, Giuberti G, Zappavigna S, Perdonà S, Facchini G, Sperlongano P, et al. Chondroitin sulphate enhances the antitumor activity of gemcitabine and mitomycin-C in bladder cancer cells with different mechanisms. Oncol Rep. 2012;27:409-15 pubmed publisher
western blot; human; 1:2000	Kasman L, Lu P, Voelkel Johnson C. The histone deacetylase inhibitors depsipeptide and MS-275, enhance TRAIL gene therapy of LNCaP prostate cancer cells without adverse effects in normal prostate epithelial cells. Cancer Gene Ther. 2007;14:327-34 pubmed
	Salva K, Kim Y, Rahbar Z, Wood G. Epigenetically Enhanced PDT Induces Significantly Higher Levels of Multiple Extrinsic Pathway Apoptotic Factors than Standard PDT, Resulting in Greater Extrinsic and Overall Apoptosis of Cutaneous T-cell Lymphoma. Photochem Photobiol. 2018;94:1058-1065 pubmed publisher
	Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, et al. Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma. Clin Cancer Res. 2016;22:1138-49 pubmed publisher
	Weiss R, Laengle J, Sachet M, Shurygina A, Kiselev O, Egorov A, et al. Interleukin-24 inhibits influenza A virus replication in vitro through induction of toll-like receptor 3 dependent apoptosis. Antiviral Res. 2015;123:93-104 pubmed publisher
	Sun J, Luo H, Nie W, Xu X, Miao X, Huang F, et al. Protective effect of RIP and c-FLIP in preventing liver cancer cell apoptosis induced by TRAIL. Int J Clin Exp Pathol. 2015;8:6519-25 pubmed
	Aredia F, Giansanti V, Mazzini G, Savio M, Ortiz L, Jaadane I, et al. Multiple effects of the Na(+)/H (+) antiporter inhibitor HMA on cancer cells. Apoptosis. 2013;18:1586-98 pubmed publisher
	Kota V, Dhople V, Fullbright G, Smythe N, Szulc Z, Bielawska A, et al. 2'-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells. J Proteome Res. 2013;12:4366-75 pubmed publisher
	Horova V, Hradilova N, Jelínková I, Koc M, Svadlenka J, Brazina J, et al. Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes. FEBS J. 2013;280:3436-50 pubmed publisher
	Böing A, Stap J, Hau C, Afink G, Ris Stalpers C, Reits E, et al. Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles. Biochim Biophys Acta. 2013;1833:1844-52 pubmed publisher
	Hossain A, Radwan F, Doonan B, God J, Zhang L, Bell P, et al. A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma. Apoptosis. 2012;17:1066-78 pubmed publisher
	Coupienne I, Fettweis G, Piette J. RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. Lasers Surg Med. 2011;43:557-64 pubmed publisher
	Xu D, Meyer F, Ehlers E, Blasnitz L, Zhang L. Interferon regulatory factor 4 (IRF-4) targets IRF-5 to regulate Epstein-Barr virus transformation. J Biol Chem. 2011;286:18261-7 pubmed publisher
	Coupienne I, Bontems S, Dewaele M, Rubio N, Habraken Y, Fulda S, et al. NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy. Biochem Pharmacol. 2011;81:606-16 pubmed publisher
	Goval J, Thielen C, Bourguignon C, Greimers R, Dejardin E, Choi Y, et al. The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP. Haematologica. 2008;93:1169-77 pubmed publisher

product information

Product ID :

ALX-804-305

Catalog Number :

ALX-804-305-C100

Product Name :

Caspase-3 monoclonal antibody (31A1067)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

List Price (USD) :

307 USD

list of Pubmed id :

26367324, 26261530, 23996609, 23987666, 23678861, 23531593, 22847295, 22057483, 22052369, 21454650

Image Legend 4 :

Figure 2: Western blot analysis of Caspase-3 in multiple human tissues using MAb to Caspase-3 (31A1067) (Prod. No. ALX-804-305) at 2µg/ml. Tissues shown are A) brain, B) heart, C) intestine, D) kidney, E) liver, F) lung, G) muscle, H) stomach, I) spleen, J) ovary, and K) testis.

Image Legend 5 :

Figure 1: Western blot analysis for detection of Caspase-3 activation in HeLa cells. Cells were treated with 2mM staurosporine for different time periods. Caspase-3 activation is determined by cleavage of procaspase-3, which generates 17 and 12kDa, larger and smaller catalytic subunit, respectively.

Clone :

31A1067

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse, Rat

Immunogen :

Recombinant human caspase-3.

Specificity :

Recognizes procaspase-3 and cleaved 17kDa catalytic subunit of caspase-3. Recognizes an epitope in the large (17kDa) domain subunit of caspase-3.

Buffer :

Liquid. In PBS containing 0.05% BSA and 0.05% sodium azide.

Application Summary :

IHC (FS), IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage