product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
TRAIL-R1 (human) monoclonal antibody (HS101) (FITC conjugate)
catalog :
ALX-804-297F-T100
quantity :
100 tests
price :
443 USD
clonality :
monoclonal
host :
mouse
conjugate :
FITC
clone name :
HS101
reactivity :
human
application :
immunocytochemistry, flow cytometry
more info or order :
Enzo Life Sciences product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; fig 4
De Toni E, Ziesch A, Rizzani A, Török H, Hocke S, Lu S, et al. Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis. Oncotarget. 2016;7:9477-90 pubmed publisher
Mucha S, Rizzani A, Gerbes A, Camaj P, Thasler W, Bruns C, et al. JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand. Gut. 2009;58:688-98 pubmed publisher
Izeradjene K, Douglas L, Delaney A, Houghton J. Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex. Cancer Res. 2004;64:8036-44 pubmed
Ganten T, Haas T, Sykora J, Stahl H, Sprick M, Fas S, et al. Enhanced caspase-8 recruitment to and activation at the DISC is critical for sensitisation of human hepatocellular carcinoma cells to TRAIL-induced apoptosis by chemotherapeutic drugs. Cell Death Differ. 2004;11:S86-96 pubmed
Hopkins-Donaldson S, Ziegler A, Kurtz S, Bigosch C, Kandioler D, Ludwig C, et al. Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation. Cell Death Differ. 2003;10:356-64 pubmed
Contassot E, Kerl K, Roques S, Shane R, Gaide O, Dupuis M, et al. Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression. Blood. 2008;111:4780-7 pubmed publisher
Secchiero P, Melloni E, Heikinheimo M, Mannisto S, Di Pietro R, Iacone A, et al. TRAIL regulates normal erythroid maturation through an ERK-dependent pathway. Blood. 2004;103:517-22 pubmed
De Toni E, Kuntzen C, Gerbes A, Thasler W, Sonuc N, Mucha S, et al. P60-c-src suppresses apoptosis through inhibition of caspase 8 activation in hepatoma cells, but not in primary hepatocytes. J Hepatol. 2007;46:682-91 pubmed
Washburn B, Weigand M, Grosse-Wilde A, Janke M, Stahl H, Rieser E, et al. TNF-related apoptosis-inducing ligand mediates tumoricidal activity of human monocytes stimulated by Newcastle disease virus. J Immunol. 2003;170:1814-21 pubmed
Tecchio C, Huber V, Scapini P, Calzetti F, Margotto D, Todeschini G, et al. IFNalpha-stimulated neutrophils and monocytes release a soluble form of TNF-related apoptosis-inducing ligand (TRAIL/Apo-2 ligand) displaying apoptotic activity on leukemic cells. Blood. 2004;103:3837-44 pubmed
Wachter T, Sprick M, Hausmann D, Kerstan A, McPherson K, Stassi G, et al. cFLIPL inhibits tumor necrosis factor-related apoptosis-inducing ligand-mediated NF-kappaB activation at the death-inducing signaling complex in human keratinocytes. J Biol Chem. 2004;279:52824-34 pubmed
product information
Product ID :
ALX-804-297F
Catalog Number :
ALX-804-297F-T100
Product Name :
TRAIL-R1 (human) monoclonal antibody (HS101) (FITC conjugate)
Host species :
Mouse
Clonality :
Monoclonal
Conjugation :
FITC
Product Type :
Antibody
Size :
100 tests
List Price (USD) :
443 USD
list of Pubmed id :
19106147, 18314443, 17224200, 15520213, 15459191, 15105837, 14726404, 12969966, 12700635, 12574346
Clone :
HS101
Isotype :
IgG1
SPECIES REACTIVITY :
Human
ALTnames :
TRAIL receptor 1, Apo-2, CD261, DR4, Death receptor 4, TNFRSF 10A, TNF-related apoptosis-inducing ligand receptor 1, Tumor necrosis factor receptor superfamily member 10A
Immunogen :
Recombinant human TRAIL-R1.
Buffer :
Liquid. 50µg in PBS containing 0.09% sodium azide.
Application Summary :
FC, ICC
Storage :
+4°C
more info or order :
Enzo Life Sciences product webpage
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.