Phosphoserine monoclonal antibody (16B4) | Enzo Life Sciences ALX-804-167-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Phosphoserine monoclonal antibody (16B4)

catalog :

ALX-804-167-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

16B4

application :

western blot, ELISA, immunoprecipitation

citations: 12

Reference
Krishnan H, Retzbach E, Ramirez M, Liu T, Li H, Miller W, et al. PKA and CDK5 can phosphorylate specific serines on the intracellular domain of podoplanin (PDPN) to inhibit cell motility. Exp Cell Res. 2015;335:115-22 pubmed publisher
Jamal S, Cheriyan V, Muthu M, Munie S, Levi E, Ashour A, et al. CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLoS ONE. 2014;9:e89146 pubmed publisher
Alvarado Kristensson M, Andersson T. Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3. J Biol Chem. 2005;280:6238-44 pubmed
Alvarado Kristensson M, Melander F, Leandersson K, Ronnstrand L, Wernstedt C, Andersson T. p38-MAPK signals survival by phosphorylation of caspase-8 and caspase-3 in human neutrophils. J Exp Med. 2004;199:449-58 pubmed
Gardai S, Hildeman D, Frankel S, Whitlock B, Frasch S, Borregaard N, et al. Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J Biol Chem. 2004;279:21085-95 pubmed
Bendt A, Burkovski A, Schaffer S, Bott M, Farwick M, Hermann T. Towards a phosphoproteome map of Corynebacterium glutamicum. Proteomics. 2003;3:1637-46 pubmed
LaFevre Bernt M, Ellerby L. Kennedy's disease. Phosphorylation of the polyglutamine-expanded form of androgen receptor regulates its cleavage by caspase-3 and enhances cell death. J Biol Chem. 2003;278:34918-24 pubmed
Tisdale E. Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway. J Biol Chem. 2002;277:3334-41 pubmed
Trockenbacher A, Suckow V, Foerster J, Winter J, Krauss S, Ropers H, et al. MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation. Nat Genet. 2001;29:287-94 pubmed
Suer S, Sickmann A, Meyer H, Herberg F, Heilmeyer L. Human phosphatidylinositol 4-kinase isoform PI4K92. Expression of the recombinant enzyme and determination of multiple phosphorylation sites. Eur J Biochem. 2001;268:2099-106 pubmed
Martelli A, Billi A, Manzoli L, Faenza I, Aluigi M, Falconi M, et al. Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation. FEBS Lett. 2000;486:230-6 pubmed
Ducret C, Maira S, Lutz Y, Wasylyk B. The ternary complex factor Net contains two distinct elements that mediate different responses to MAP kinase signalling cascades. Oncogene. 2000;19:5063-72 pubmed

product information

Product ID :

ALX-804-167

Catalog Number :

ALX-804-167-C100

Product Name :

Phosphoserine monoclonal antibody (16B4)

Host species :

Mouse

Clonality :

Monoclonal

Antigen modification :

Phosphorylated

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

15569672, 14970175, 14766748, 12923788, 12824190, 11724794, 11685209, 11277933, 11119709, 11042694

Clone :

16B4

Isotype :

IgM

SPECIES REACTIVITY :

Species independent

Immunogen :

Phosphoserine containing peptides conjugated to KLH.

Specificity :

Recognizes a broad range of serine-phosphorylated proteins in crude cell extracts, strongly interacting with pSK and pSP motifs, thus specifically recognizing substrates of MAP/SAP kinases and CDC kinases. Please note that phosphoserine detection by MAbs always depends on the surrounding aa sequence.

Buffer :

Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.

Application Summary :

ELISA, IP, WB

Storage :

-20°C