product summary
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company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
mtHSP70 monoclonal antibody (JG1)
catalog :
ALX-804-077-R100
quantity :
100 µl
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JG1
reactivity :
human, mouse, dogs
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3a
Tamura Y, Matsunaga Y, Kitaoka Y, Hatta H. Effects of Heat Stress Treatment on Age-dependent Unfolded Protein Response in Different Types of Skeletal Muscle. J Gerontol A Biol Sci Med Sci. 2017;72:299-308 pubmed publisher
  • western blot; mouse; loading ...; fig s1
Kim H, Nagano Y, Choi S, Park S, Kim H, Yao T, et al. HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation. Biochem Biophys Res Commun. 2015;464:1235-1240 pubmed publisher
  • western blot; human
Van Beersel G, Tihon E, Demine S, Hamer I, Jadot M, Arnould T. Different molecular mechanisms involved in spontaneous and oxidative stress-induced mitochondrial fragmentation in tripeptidyl peptidase-1 (TPP-1)-deficient fibroblasts. Biosci Rep. 2013;33:e00023 pubmed publisher
  • western blot; human
Rossi M, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, et al. Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem. 2009;284:31616-24 pubmed publisher
Giansanti V, Rodriguez G, Savoldelli M, Gioia R, Forlino A, Mazzini G, et al. Characterization of stress response in human retinal epithelial cells. J Cell Mol Med. 2013;17:103-15 pubmed publisher
Goetz J, Genty H, St Pierre P, Dang T, Joshi B, Sauve R, et al. Reversible interactions between smooth domains of the endoplasmic reticulum and mitochondria are regulated by physiological cytosolic Ca2+ levels. J Cell Sci. 2007;120:3553-64 pubmed
Orsini F, Migliaccio E, Moroni M, Contursi C, Raker V, Piccini D, et al. The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential. J Biol Chem. 2004;279:25689-95 pubmed
Williams S, Valnot I, Rustin P, Taanman J. Cytochrome c oxidase subassemblies in fibroblast cultures from patients carrying mutations in COX10, SCO1, or SURF1. J Biol Chem. 2004;279:7462-9 pubmed
Green J, Gu L, Ifkovits C, Kaumaya P, Conrad S, Pierce S. Generation and characterization of monoclonal antibodies specific for members of the mammalian 70-kDa heat shock protein family. Hybridoma. 1995;14:347-54 pubmed
product information
Product ID :
ALX-804-077
Catalog Number :
ALX-804-077-R100
Product Name :
mtHSP70 monoclonal antibody (JG1)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µl
list of Pubmed id :
26210454, 23205553, 17895372, 15078873, 14607829, 8522346
Clone :
JG1
Isotype :
IgG3
SPECIES REACTIVITY :
Human, Mouse, Monkey, Dog
ALTnames :
Mortalin, Heat shock protein 70 (mitochondrial), GRP75
Immunogen :
Synthetic peptide corresponding to C-terminal aa 615-633 (G615SGSSGTGEQKEDQKEEKQ633) of mouse mtHSP70 (mitochondrial heat shock protein 70).
Buffer :
Liquid. Ascites diluted in PBS containing 0.05% sodium azide.
Uses :
Detects a band of ~75kDa by Western blot.
Application Summary :
ICC, IP, WB
Storage :
-20°C
more info or order :
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.