EGF receptor (human) monoclonal antibody (13G8) | Enzo Life Sciences ALX-804-064-C100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

EGF receptor (human) monoclonal antibody (13G8)

catalog :

ALX-804-064-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13G8

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

more info or order :

Enzo Life Sciences product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 3a-c	Arena S, Siravegna G, Mussolin B, Kearns J, Wolf B, Misale S, et al. MM-151 overcomes acquired resistance to cetuximab and panitumumab in colorectal cancers harboring EGFR extracellular domain mutations. Sci Transl Med. 2016;8:324ra14 pubmed publisher
western blot; human; fig 7a	Misale S, Bozic I, Tong J, Peraza Penton A, Lallo A, Baldi F, et al. Vertical suppression of the EGFR pathway prevents onset of resistance in colorectal cancers. Nat Commun. 2015;6:8305 pubmed publisher
	Lamba S, Russo M, Sun C, Lazzari L, Cancelliere C, Grernrum W, et al. RAF suppression synergizes with MEK inhibition in KRAS mutant cancer cells. Cell Rep. 2014;8:1475-83 pubmed publisher
	Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature. 2012;486:532-6 pubmed publisher
	Weyergang A, Selbo P, Berg K. Y1068 phosphorylation is the most sensitive target of disulfonated tetraphenylporphyrin-based photodynamic therapy on epidermal growth factor receptor. Biochem Pharmacol. 2007;74:226-35 pubmed

product information

Product ID :

ALX-804-064

Catalog Number :

ALX-804-064-C100

Product Name :

EGF receptor (human) monoclonal antibody (13G8)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

26392303, 25199829, 22722830, 17531956

Clone :

13G8

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

Epidermal growth factor receptor, EGFR, HER-1

Immunogen :

Synthetic peptide corresponding to aa 1165-1186 of EGF receptor (epidermal growth factor receptor) conjugated to KLH.

Specificity :

Recognizes the C-terminus of the EGF receptor (aa 1165-1186). Recognition is independent of phosphorylation of Tyr1173.

Buffer :

Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.

Application Summary :

ELISA, ICC, IP, WB, Luminex

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage