Vitamin D3 receptor monoclonal antibody (9A7) | Enzo Life Sciences ALX-804-021-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Vitamin D3 receptor monoclonal antibody (9A7)

catalog :

ALX-804-021-C100

quantity :

100 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

9A7

reactivity :

human, mouse, rat, chicken

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation

citations: 9

Reference
Lee W, Jena S, Doherty D, Ventakesh J, Schimdt J, Furmick J, et al. Sentrin/SUMO specific proteases as novel tissue-selective modulators of vitamin D receptor-mediated signaling. PLoS ONE. 2014;9:e89506 pubmed publisher
Michigami T, Suga A, Yamazaki M, Shimizu C, Cai G, Okada S, et al. Identification of amino acid sequence in the hinge region of human vitamin D receptor that transfers a cytosolic protein to the nucleus. J Biol Chem. 1999;274:33531-8 pubmed
Morrison N, Qi J, Tokita A, Kelly P, Crofts L, Nguyen T, et al. Prediction of bone density from vitamin D receptor alleles. Nature. 1994;367:284-7 pubmed
Pike J, Donaldson C, Marion S, Haussler M. Development of hybridomas secreting monoclonal antibodies to the chicken intestinal 1 alpha,25-dihydroxyvitamin D3 receptor. Proc Natl Acad Sci U S A. 1982;79:7719-23 pubmed
Pike J, Marion S, Donaldson C, Haussler M. Serum and monoclonal antibodies against the chick intestinal receptor for 1,25-dihydroxyvitamin D3. Generation by a preparation enriched in a 64,000-dalton protein. J Biol Chem. 1983;258:1289-96 pubmed
Haussler M, Mangelsdorf D, Komm B, Terpening C, Yamaoka K, Allegretto E, et al. Molecular biology of the vitamin D hormone. Recent Prog Horm Res. 1988;44:263-305 pubmed
Clemens T, Garrett K, Zhou X, Pike J, Haussler M, Dempster D. Immunocytochemical localization of the 1,25-dihydroxyvitamin D3 receptor in target cells. Endocrinology. 1988;122:1224-30 pubmed
Milde P, Merke J, Ritz E, Haussler M, Rauterberg E. Immunohistochemical detection of 1,25-dihydroxyvitamin D3 receptors and estrogen receptors by monoclonal antibodies: comparison of four immunoperoxidase methods. J Histochem Cytochem. 1989;37:1609-17 pubmed
MacDonald P, Haussler C, Terpening C, Galligan M, Reeder M, Whitfield G, et al. Baculovirus-mediated expression of the human vitamin D receptor. Functional characterization, vitamin D response element interactions, and evidence for a receptor auxiliary factor. J Biol Chem. 1991;266:18808-13 pubmed

product information

Product ID :

ALX-804-021

Catalog Number :

ALX-804-021-C100

Product Name :

Vitamin D3 receptor monoclonal antibody (9A7)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

24586832, 10559238, 8161378, 6296847, 6296076, 2851156, 2831024, 2553800, 1655763

Clone :

9A7

Isotype :

IgG2b

SPECIES REACTIVITY :

Human, Mouse, Rat, Hamster, Fish, Chicken, Amphibian

ALTnames :

VDR, 1,25-Dihydroxyvitamin D3 receptor

Immunogen :

Partially purified chicken intestinal cytoplasmic VDR (vitamin D3 receptor).

Specificity :

Recognizes the occupied and unoccupied forms of VDR. Recognizes an epitope between aa 89 and 105 of human VDR.

Buffer :

Liquid. Purified antibody containing 0.05% sodium azide.

Uses :

In avians detects bands of ~58kDa and ~60kDa by Western blot, while in mammalian species the VDRs appear as a single band within the ~52-55kDa range.

Application Summary :

ICC, IP, WB, Gel Supershift, ChIP

Storage :

-20°C