B4GALT1 (human) monoclonal antibody (GT2/36/118) | Enzo Life Sciences ALX-803-339-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

B4GALT1 (human) monoclonal antibody (GT2/36/118)

catalog :

ALX-803-339-C050

quantity :

50 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

GT2/36/118

reactivity :

human

application :

western blot, immunocytochemistry

citations: 10

Reference
Reynders E, Foulquier F, Leao Teles E, Quelhas D, Morelle W, Rabouille C, et al. Golgi function and dysfunction in the first COG4-deficient CDG type II patient. Hum Mol Genet. 2009;18:3244-56 pubmed publisher
Duwel M, Ungewickell E. Clathrin-dependent association of CVAK104 with endosomes and the trans-Golgi network. Mol Biol Cell. 2006;17:4513-25 pubmed
Altan Bonnet N, Sougrat R, Liu W, Snapp E, Ward T, Lippincott Schwartz J. Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities. Mol Biol Cell. 2006;17:990-1005 pubmed
García Vallejo J, van Dijk W, van Die I, Gringhuis S. Tumor necrosis factor-alpha up-regulates the expression of beta1,4-galactosyltransferase I in primary human endothelial cells by mRNA stabilization. J Biol Chem. 2005;280:12676-82 pubmed
Stöckli J, Rohrer J. The palmitoyltransferase of the cation-dependent mannose 6-phosphate receptor cycles between the plasma membrane and endosomes. Mol Biol Cell. 2004;15:2617-26 pubmed
Salcedo S, Holden D. SseG, a virulence protein that targets Salmonella to the Golgi network. EMBO J. 2003;22:5003-14 pubmed
Rohrer J, Kornfeld R. Lysosomal hydrolase mannose 6-phosphate uncovering enzyme resides in the trans-Golgi network. Mol Biol Cell. 2001;12:1623-31 pubmed
Hammond A, Glick B. Dynamics of transitional endoplasmic reticulum sites in vertebrate cells. Mol Biol Cell. 2000;11:3013-30 pubmed
Moore S, Bauvy C, Codogno P. Endoplasmic reticulum-to-cytosol transport of free polymannose oligosaccharides in permeabilized HepG2 cells. EMBO J. 1995;14:6034-42 pubmed
Nilsson T, Hoe M, Slusarewicz P, Rabouille C, Watson R, Hunte F, et al. Kin recognition between medial Golgi enzymes in HeLa cells. EMBO J. 1994;13:562-74 pubmed

product information

Product ID :

ALX-803-339

Catalog Number :

ALX-803-339-C050

Product Name :

B4GALT1 (human) monoclonal antibody (GT2/36/118)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

50 µg

list of Pubmed id :

19494034, 16914521, 16314396, 15668241, 15034140, 14517239, 11408573, 10982397, 8846796, 8313901

Clone :

GT2/36/118

Isotype :

IgG2b

SPECIES REACTIVITY :

Human

Background :

β-1,4-Galactosyltransferase 1 (B4GALT1) is one of seven B4GALT genes. Human B4GALT1 encodes a type II membrane protein, which is ubiquitously expressed and involved in glycoconjugate biosynthesis. A soluble form (aa 78 to 398), derived from proteolytic cleavage, is a component of lactose synthase in milk that also contains α-lactalbumin. The amino acid sequence of human B4GALT1 is 88%, 87% and 71% identical to that of rat, mouse/canine and chicken.Defects in B4GALT1 are the cause of multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency.

ALTnames :

β-1,4-Galactosyltransferase 1, GGTB2

Immunogen :

Recombinant human B4GALT1

Buffer :

Liquid. Contains 150µg/ml BSA.

Application Summary :

ICC, WB

Storage :

-20°C