This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
MD-2 (human) monoclonal antibody (10A8)
catalog :
ALX-803-324-C100
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10A8
reactivity :
human
application :
western blot, ELISA
citations: 1
Reference
Viriyakosol S, McCray P, Ashbaugh M, Chu J, Jia H, Weiss J, et al. Characterization of monoclonal antibodies to human soluble MD-2 protein. Hybridoma (Larchmt). 2006;25:349-57 pubmed
product information
Product ID :
ALX-803-324
Catalog Number :
ALX-803-324-C100
Product Name :
MD-2 (human) monoclonal antibody (10A8)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
100 µg
list of Pubmed id :
17203997
Clone :
10A8
Isotype :
IgG1
SPECIES REACTIVITY :
Human
Background :
The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. Toll-like receptor 4 (TLR4), the principal signaling receptor for lipopolysaccharide (LPS) in mammals, requires the binding of MD-2 to its extracellular domain for maximal responsiveness. MD-2 enables TLR4 to respond to a wide variety of LPS partial structures, Gram-negative bacteria, and Gram-positive lipoteichoic acid, but not to Gram-positive bacteria, peptidoglycan, and lipopeptide.
ALTnames :
LY96, Lymphocyte antigen 96, ESOP-1
Immunogen :
Recombinant human MD-2.
Specificity :
Recognizes all forms of soluble human MD-2, but not membrane bound MD-2.
Buffer :
Liquid. In PBS containing 0.02% sodium azide.
Application Summary :
ELISA, WB
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.