Furin convertase (human) monoclonal antibody (MON-152) | Enzo Life Sciences ALX-803-017-R100 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Furin convertase (human) monoclonal antibody (MON-152)

catalog :

ALX-803-017-R100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MON-152

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Enzo Life Sciences product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:750; loading ...; fig 2b	Gechijian L, Buckley D, Lawlor M, Reyes J, Paulk J, Ott C, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nat Chem Biol. 2018;14:405-412 pubmed publisher
western blot; human; loading ...; fig 4	Hoffmann H, Schneider W, Blomen V, Scull M, Hovnanian A, Brummelkamp T, et al. Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread. Cell Host Microbe. 2017;22:460-470.e5 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig 1c western blot; mouse; loading ...; fig 1a	Bassi D, Zhang J, Renner C, Klein Szanto A. Targeting proprotein convertases in furin-rich lung cancer cells results in decreased in vitro and in vivo growth. Mol Carcinog. 2017;56:1182-1188 pubmed publisher
western blot; human; 1:750; loading ...; fig 1b	Jaaks P, D Alessandro V, Grob N, Büel S, Hajdin K, Schafer B, et al. The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion. PLoS ONE. 2016;11:e0161396 pubmed publisher
	Oksanen A, AittomÃ¤ki S, Jankovic D, Ortutay Z, Pulkkinen K, HÃ¤mÃ¤lÃ¤inen S, et al. Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii. J Immunol. 2014;193:5470-9 pubmed publisher
	Mukherjee S, Dowd K, Manhart C, Ledgerwood J, Durbin A, Whitehead S, et al. Mechanism and significance of cell type-dependent neutralization of flaviviruses. J Virol. 2014;88:7210-20 pubmed publisher
	Kappert K, Meyborg H, Fritzsche J, Urban D, Krüger J, Wellnhofer E, et al. Proprotein convertase subtilisin/kexin type 3 promotes adipose tissue-driven macrophage chemotaxis and is increased in obesity. PLoS ONE. 2013;8:e70542 pubmed publisher
	Urban D, Lorenz J, Meyborg H, Ghosh S, Kintscher U, Kaufmann J, et al. Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor. J Biochem. 2013;153:197-207 pubmed publisher
	Zhu J, Declercq J, Roucourt B, Ghassabeh G, Meulemans S, Kinne J, et al. Generation and characterization of non-competitive furin-inhibiting nanobodies. Biochem J. 2012;448:73-82 pubmed publisher
	Turpeinen H, Raitoharju E, Oksanen A, Oksala N, Levula M, Lyytikäinen L, et al. Proprotein convertases in human atherosclerotic plaques: the overexpression of FURIN and its substrate cytokines BAFF and APRIL. Atherosclerosis. 2011;219:799-806 pubmed publisher
	Brown S, Ghosh A, Winkles J. Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. J Biol Chem. 2010;285:17432-41 pubmed publisher
	Furundzija V, Fritzsche J, Kaufmann J, Meyborg H, Fleck E, Kappert K, et al. IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling. Biochem Biophys Res Commun. 2010;394:786-91 pubmed publisher
	Leonhardt R, Fiegl D, Rufer E, Karger A, Bettin B, Knittler M. Post-endoplasmic reticulum rescue of unstable MHC class I requires proprotein convertase PC7. J Immunol. 2010;184:2985-98 pubmed publisher
	Koo B, Longpre J, Somerville R, Alexander J, Leduc R, Apte S. Cell-surface processing of pro-ADAMTS9 by furin. J Biol Chem. 2006;281:12485-94 pubmed

product information

Product ID :

ALX-803-017

Catalog Number :

ALX-803-017-R100

Product Name :

Furin convertase (human) monoclonal antibody (MON-152)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

list of Pubmed id :

25355923, 24741083, 23936445, 23172302, 22920187, 21889147, 20385556, 20230795, 20164418, 16537537

Clone :

MON-152

Isotype :

IgG1

SPECIES REACTIVITY :

Human

Immunogen :

Recombinant human furin.

Specificity :

Recognizes an epitope in the cysteine-rich region of human furin convertase.

Buffer :

Liquid. Ascites. Contains no preservatives.

Application Summary :

ICC, IP, WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage