Furin convertase (R2) monoclonal antibody (MON-148) | Enzo Life Sciences ALX-803-015-R100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Furin convertase (R2) monoclonal antibody (MON-148)

catalog :

ALX-803-015-R100

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MON-148

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 10

Reference
Zhu J, Van de Ven W, Vermorken A. Polyphenols with indirect proprotein convertase inhibitory activity. Int J Oncol. 2013;43:947-55 pubmed publisher
Zhu J, Declercq J, Roucourt B, Ghassabeh G, Meulemans S, Kinne J, et al. Generation and characterization of non-competitive furin-inhibiting nanobodies. Biochem J. 2012;448:73-82 pubmed publisher
Gawlik K, Remacle A, Shiryaev S, Golubkov V, Ouyang M, Wang Y, et al. A femtomol range FRET biosensor reports exceedingly low levels of cell surface furin: implications for the processing of anthrax protective antigen. PLoS ONE. 2010;5:e11305 pubmed publisher
Koo B, Kim H, Park M, Jeon O, Kim D. Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases. FEBS J. 2009;276:6271-84 pubmed publisher
Jayakumar A, Kang Y, Henderson Y, Mitsudo K, Liu X, Briggs K, et al. Consequences of C-terminal domains and N-terminal signal peptide deletions on LEKTI secretion, stability, and subcellular distribution. Arch Biochem Biophys. 2005;435:89-102 pubmed
Plaimauer B, Mohr G, Wernhart W, Himmelspach M, Dorner F, Schlokat U. 'Shed' furin: mapping of the cleavage determinants and identification of its C-terminus. Biochem J. 2001;354:689-95 pubmed
Cameron A, Appel J, Houghten R, Lindberg I. Polyarginines are potent furin inhibitors. J Biol Chem. 2000;275:36741-9 pubmed
Van de Ven W, Roebroek A, Van Duijnhoven H. Structure and function of eukaryotic proprotein processing enzymes of the subtilisin family of serine proteases. Crit Rev Oncog. 1993;4:115-36 pubmed
Creemers J, Siezen R, Roebroek A, Ayoubi T, Huylebroeck D, Van de Ven W. Modulation of furin-mediated proprotein processing activity by site-directed mutagenesis. J Biol Chem. 1993;268:21826-34 pubmed
Van Duijnhoven H, Creemers J, Kranenborg M, Timmer E, Groeneveld A, van den Ouweland A, et al. Development and characterization of a panel of monoclonal antibodies against the novel subtilisin-like proprotein processing enzyme furin. Hybridoma. 1992;11:71-86 pubmed

product information

Product ID :

ALX-803-015

Catalog Number :

ALX-803-015-R100

Product Name :

Furin convertase (R2) monoclonal antibody (MON-148)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µl

list of Pubmed id :

23835774, 22920187, 20585585, 19780834, 15680911, 11237874, 10958789, 8420571, 8408037, 1737642

Clone :

MON-148

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse

Immunogen :

Recombinant human furin.

Specificity :

Recognizes epitope region 2 (R2) in the catalytic domain of furin convertase.

Buffer :

Liquid. Ascites fluid. Contains no preservatives.

Application Summary :

ICC, IP, WB

Storage :

-20°C