Prolactin receptor monoclonal antibody (U5) | Enzo Life Sciences ALX-803-005-C100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Prolactin receptor monoclonal antibody (U5)

catalog :

ALX-803-005-C100

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

U5

The same clone is also sold as:

Abcam: ab2772
Novus Biologicals: NB300-561
Invitrogen: MA1-610

reactivity :

human, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 4

Reference
De Petrocellis L, Melck D, Palmisano A, Bisogno T, Laezza C, Bifulco M, et al. The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation. Proc Natl Acad Sci U S A. 1998;95:8375-80 pubmed
Perrot Applanat M, Gualillo O, Buteau H, Edery M, Kelly P. Internalization of prolactin receptor and prolactin in transfected cells does not involve nuclear translocation. J Cell Sci. 1997;110 ( Pt 9):1123-32 pubmed
Royster M, Driscoll P, Kelly P, Freemark M. The prolactin receptor in the fetal rat: cellular localization of messenger ribonucleic acid, immunoreactive protein, and ligand-binding activity and induction of expression in late gestation. Endocrinology. 1995;136:3892-900 pubmed
Okamura H, Zachwieja J, Raguet S, Kelly P. Characterization and applications of monoclonal antibodies to the prolactin receptor. Endocrinology. 1989;124:2499-508 pubmed

product information

Product ID :

ALX-803-005

Catalog Number :

ALX-803-005-C100

Product Name :

Prolactin receptor monoclonal antibody (U5)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

100 µg

list of Pubmed id :

9653194, 9175708, 7649097, 2707162

Clone :

Isotype :

IgG1

SPECIES REACTIVITY :

Human, Rat, Rabbit, Porcine

Background :

Prolactin (PRL) is a hormone involved in a variety of important functions including ion transport and osmoregulation, stimulation of milk, protein synthesis as well as the regulation of numerous reproductive functions. PRL exerts its influence on different cell types through a signal transduction pathway which begins with the binding of the hormone to a transmembrane PRL receptor. Immunoreactive PRL receptor, a member of the cytokine receptor family, varies in size (short and long forms) with tissue source and species, from ~40 kDa to 100 kDa. The PRL receptor consists of at least three separate domains: an extracellular region with 5 cysteines which contains the prolactin binding site, a single transmembrane domain and a cytoplasmic region, the length of which appears to influence ligand binding and regulate cellular function.

ALTnames :

PRL receptor

Immunogen :

Purified rat liver prolactin receptor.

Specificity :

Recognizes the extracellular domain of the prolactin receptor.

Buffer :

Lyophilized. Contains 0.05% sodium azide.

Uses :

Detects bands of ~40kDa and of ~100kDa representing both the short and the long forms of the prolactin receptor. Does not inhibit the interaction of prolactin with the receptor.

Application Summary :

FC, ICC, IHC (FS), IHC (PS), IP, WB

Storage :

-20°C