MRP4 monoclonal antibody (M4I-10) | Enzo Life Sciences ALX-801-038-C150 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MRP4 monoclonal antibody (M4I-10)

catalog :

ALX-801-038-C150

quantity :

150 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

M4I-10

The same clone is also sold as:

Santa Cruz Biotechnology: sc-59614
Invitrogen: MA1-35681
OriGene: AM32023SU-N
Abcam: ab15602
Abnova: MAB3400

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

more info or order :

Enzo Life Sciences product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 7a	Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed publisher
western blot; human; loading ...; fig 2d	Csandl M, Conseil G, Cole S. Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4). Drug Metab Dispos. 2016;44:857-66 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100 western blot; mouse	Aleksunes L, Xu J, Lin E, Wen X, Goedken M, Slitt A. Pregnancy represses induction of efflux transporters in livers of type I diabetic mice. Pharm Res. 2013;30:2209-20 pubmed publisher
	Miah M, Conseil G, Cole S. N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity. Biochem Biophys Res Commun. 2016;469:954-9 pubmed publisher
	Cheung L, Yu D, Neiron Z, Failes T, Arndt G, Fletcher J. Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen. Biochem Pharmacol. 2015;93:380-8 pubmed publisher
	Yang K, Pfeifer N, Hardwick R, Yue W, Stewart P, Brouwer K. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Mol Pharm. 2014;11:766-75 pubmed publisher
	Henderson M, Haber M, Porro A, Munoz M, Iraci N, Xue C, et al. ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux. J Natl Cancer Inst. 2011;103:1236-51 pubmed publisher
	Hoque M, Cole S. Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4. Cancer Res. 2008;68:4802-9 pubmed publisher
	Leggas M, Adachi M, Scheffer G, Sun D, Wielinga P, Du G, et al. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Mol Cell Biol. 2004;24:7612-21 pubmed

product information

Product ID :

ALX-801-038

Catalog Number :

ALX-801-038-C150

Product Name :

MRP4 monoclonal antibody (M4I-10)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

150 µg

list of Pubmed id :

26721430, 18559527, 15314169

Clone :

M4I-10

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

Multidrug resistance-associated protein 4, ABCC4

Immunogen :

Recombinant human MRP4 (multidrug resistance-associated protein 4) (aa 372-431).

Buffer :

Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.

Uses :

Immunocytochemistry: cytospin preparations

Application Summary :

ICC, IHC (FS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage