Breast cancer resistance protein monoclonal antibody (BXP-53) | Enzo Life Sciences ALX-801-036-C125 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

Breast cancer resistance protein monoclonal antibody (BXP-53)

catalog :

ALX-801-036-C125

quantity :

125 µg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

BXP-53

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Enzo Life Sciences product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; human	Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G. Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier. Pharm Res. 2015;32:2973-82 pubmed publisher
western blot; mouse	Aleksunes L, Xu J, Lin E, Wen X, Goedken M, Slitt A. Pregnancy represses induction of efflux transporters in livers of type I diabetic mice. Pharm Res. 2013;30:2209-20 pubmed publisher
immunocytochemistry; mouse western blot; mouse; 1:5000	Gibson C, Hossain M, Richardson J, Aleksunes L. Inflammatory regulation of ATP binding cassette efflux transporter expression and function in microglia. J Pharmacol Exp Ther. 2012;343:650-60 pubmed publisher
immunocytochemistry; rat western blot; rat	Tchaparian E, Houghton J, Uyeda C, Grillo M, Jin L. Effect of culture time on the basal expression levels of drug transporters in sandwich-cultured primary rat hepatocytes. Drug Metab Dispos. 2011;39:2387-94 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:50	Brenn A, Grube M, Peters M, Fischer A, Jedlitschky G, Kroemer H, et al. Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice. Int J Alzheimers Dis. 2011;2011:690121 pubmed publisher
	Kumar J, Wei B, Madigan J, Simpson R, Hall M, Gottesman M. Bioluminescent imaging of ABCG2 efflux activity at the blood-placenta barrier. Sci Rep. 2016;6:20418 pubmed publisher
	Bircsak K, Gupta V, Yuen P, Gorczyca L, WEINBERGER B, Vetrano A, et al. Genetic and Dietary Regulation of Glyburide Efflux by the Human Placental Breast Cancer Resistance Protein Transporter. J Pharmacol Exp Ther. 2016;357:103-13 pubmed publisher
	Chapy H, SaubamÃ©a B, Tournier N, Bourasset F, Behar Cohen F, DeclÃ¨ves X, et al. Blood-brain and retinal barriers show dissimilar ABC transporter impacts and concealed effect of P-glycoprotein on a novel verapamil influx carrier. Br J Pharmacol. 2016;173:497-510 pubmed publisher
	Salvamoser J, Avemary J, Luna Munguia H, Pascher B, Getzinger T, Pieper T, et al. Glutamate-Mediated Down-Regulation of the Multidrug-Resistance Protein BCRP/ABCG2 in Porcine and Human Brain Capillaries. Mol Pharm. 2015;12:2049-60 pubmed publisher
	Yang K, Pfeifer N, Hardwick R, Yue W, Stewart P, Brouwer K. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Mol Pharm. 2014;11:766-75 pubmed publisher
	Jonker J, Buitelaar M, Wagenaar E, van der Valk M, Scheffer G, Scheper R, et al. The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci U S A. 2002;99:15649-54 pubmed

product information

Product ID :

ALX-801-036

Catalog Number :

ALX-801-036-C125

Product Name :

Breast cancer resistance protein monoclonal antibody (BXP-53)

Host species :

Rat

Clonality :

Monoclonal

Product Type :

Antibody

Size :

125 µg

list of Pubmed id :

21660212, 12429862

Clone :

BXP-53

Isotype :

IgG2a

SPECIES REACTIVITY :

Human, Mouse

ALTnames :

BCRP, ABCG2, MXR, CD338

Immunogen :

Recombinant mouse BCRP (breast cancer resistance protein; MXR) (aa 221-394).

Specificity :

Recognizes an internal epitope of BCRP.

Buffer :

Liquid. In serum free cell culture supernatant containing 0.7% BSA and 0.1% sodium azide.

Application Summary :

ICC, IHC (FS), IHC (PS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage