product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
antibody
product name :
Breast cancer resistance protein (human) monoclonal antibody (BXP-21)
catalog :
ALX-801-029-C250
quantity :
250 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
BXP-21

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Enzo Life Sciences product webpage
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 7a
Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed publisher
  • western blot; human; 1:500
Agarwal S, Mittapalli R, Zellmer D, Gallardo J, Donelson R, Seiler C, et al. Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents. Mol Cancer Ther. 2012;11:2183-92 pubmed publisher
Rigalli J, Tocchetti G, Arana M, Villanueva S, Catania V, Theile D, et al. The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters. Cancer Lett. 2016;376:165-72 pubmed publisher
Mayati A, Le Vee M, Moreau A, Jouan E, Bucher S, Stieger B, et al. Protein kinase C-dependent regulation of human hepatic drug transporter expression. Biochem Pharmacol. 2015;98:703-17 pubmed publisher
Redaelli S, Perini P, Ceccon M, Piazza R, Rigolio R, Mauri M, et al. In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib. J Hematol Oncol. 2015;8:81 pubmed publisher
Jacob A, Potin S, Chapy H, Crete D, Glacial F, Ganeshamoorthy K, et al. Aryl hydrocarbon receptor regulates CYP1B1 but not ABCB1 and ABCG2 in hCMEC/D3 human cerebral microvascular endothelial cells after TCDD exposure. Brain Res. 2015;1613:27-36 pubmed publisher
Rigalli J, Ciriaci N, Arias A, Ceballos M, Villanueva S, Luquita M, et al. Regulation of multidrug resistance proteins by genistein in a hepatocarcinoma cell line: impact on sorafenib cytotoxicity. PLoS ONE. 2015;10:e0119502 pubmed publisher
Ellis K, Marlin J, Taylor T, Fitting S, Hauser K, Rice G, et al. The effects of human immunodeficiency virus infection on the expression of the drug efflux proteins P-glycoprotein and breast cancer resistance protein in a human intestine model. J Pharm Pharmacol. 2015;67:178-88 pubmed publisher
Cheung L, Yu D, Neiron Z, Failes T, Arndt G, Fletcher J. Identification of new MRP4 inhibitors from a library of FDA approved drugs using a high-throughput bioluminescence screen. Biochem Pharmacol. 2015;93:380-8 pubmed publisher
Venkatraman G, Benesch M, Tang X, Dewald J, McMullen T, Brindley D. Lysophosphatidate signaling stabilizes Nrf2 and increases the expression of genes involved in drug resistance and oxidative stress responses: implications for cancer treatment. FASEB J. 2015;29:772-85 pubmed publisher
Rigalli J, Perdomo V, Luquita M, Villanueva S, Arias A, Theile D, et al. Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor. PLoS Negl Trop Dis. 2012;6:e1951 pubmed publisher
Poller B, Drewe J, Krahenbuhl S, Huwyler J, Gutmann H. Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier. Cell Mol Neurobiol. 2010;30:63-70 pubmed publisher
Maliepaard M, Scheffer G, Faneyte I, van Gastelen M, Pijnenborg A, Schinkel A, et al. Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues. Cancer Res. 2001;61:3458-64 pubmed
product information
Product ID :
ALX-801-029
Catalog Number :
ALX-801-029-C250
Product Name :
Breast cancer resistance protein (human) monoclonal antibody (BXP-21)
Host species :
Mouse
Clonality :
Monoclonal
Product Type :
Antibody
Size :
250 µg
list of Pubmed id :
26462574, 19629677, 11309308
Clone :
BXP-21
Isotype :
IgG2a
SPECIES REACTIVITY :
Human
ALTnames :
MXR, BCRP, ABCG2, CD338
Immunogen :
Recombinant human BCRP (breast cancer resistance protein; MXR) (aa 271-396).
Specificity :
Recognizes an internal epitope of human BCRP.
Buffer :
Liquid. In serum free cell culture supernatant containing 0.7% BSA and 0.1% sodium azide.
Uses :
Immunocytochemistry: cytospin preparations
Application Summary :
ICC, IHC (FS), IHC (PS), WB
Storage :
-20°C
more info or order :
Enzo Life Sciences product webpage
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.