MDR3 P-glycoprotein (human) monoclonal antibody (P3II-26) | Enzo Life Sciences ALX-801-028-C125 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MDR3 P-glycoprotein (human) monoclonal antibody (P3II-26)

catalog :

ALX-801-028-C125

quantity :

125 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P3II-26

reactivity :

human, dogs

application :

western blot, immunohistochemistry, immunocytochemistry

more info or order :

Enzo Life Sciences product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 3a western blot; human; loading ...; fig 3b	Delaunay J, Bruneau A, Hoffmann B, Durand Schneider A, Barbu V, Jacquemin E, et al. Functional defect of variants in the adenosine triphosphate-binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770). Hepatology. 2017;65:560-570 pubmed publisher
immunohistochemistry; human; fig 1f	Grammatikopoulos T, Sambrotta M, Strautnieks S, Foskett P, Knisely A, Wagner B, et al. Mutations in DCDC2 (doublecortin domain containing protein 2) in neonatal sclerosing cholangitis. J Hepatol. 2016;65:1179-1187 pubmed publisher
immunocytochemistry; human; 1:35; fig 4 western blot; human; loading ...; fig 5a	Mahdi Z, Synal Hermanns U, Yoker A, Locher K, Stieger B. Role of Multidrug Resistance Protein 3 in Antifungal-Induced Cholestasis. Mol Pharmacol. 2016;90:23-34 pubmed publisher
immunocytochemistry; human western blot; human immunocytochemistry; dogs western blot; dogs	Gautherot J, Delautier D, Maubert M, Ait Slimane T, Bolbach G, Delaunay J, et al. Phosphorylation of ABCB4 impacts its function: insights from disease-causing mutations. Hepatology. 2014;60:610-21 pubmed publisher
	Gautherot J, Claudel T, Cuperus F, Fuchs C, Falguières T, Trauner M. Thyroid hormone receptor β1 stimulates ABCB4 to increase biliary phosphatidylcholine excretion in mice. J Lipid Res. 2018;59:1610-1619 pubmed publisher
	Venot Q, Delaunay J, Fouassier L, Delautier D, FalguiÃ¨res T, Housset C, et al. A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression. PLoS ONE. 2016;11:e0146962 pubmed publisher
	Delaunay J, Durand Schneider A, Dossier C, FalguiÃ¨res T, Gautherot J, Davit Spraul A, et al. A functional classification of ABCB4 variations causing progressive familial intrahepatic cholestasis type 3. Hepatology. 2016;63:1620-31 pubmed publisher
	Vij M, Safwan M, Shanmugam N, Rela M. Liver pathology in severe multidrug resistant 3 protein deficiency: a series of 10 pediatric cases. Ann Diagn Pathol. 2015;19:277-82 pubmed publisher
	Scheffer G, Kool M, Heijn M, de Haas M, Pijnenborg A, Wijnholds J, et al. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res. 2000;60:5269-77 pubmed

product information

Product ID :

ALX-801-028

Catalog Number :

ALX-801-028-C125

Product Name :

MDR3 P-glycoprotein (human) monoclonal antibody (P3II-26)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

125 µg

list of Pubmed id :

26117383, 11016657

Clone :

P3II-26

Isotype :

IgG2b

SPECIES REACTIVITY :

Human

ALTnames :

ABCB4

Immunogen :

MDR3 P-glycoprotein fragment (aa 629-692).

Buffer :

Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.

Uses :

Immunocytochemistry: cytospin preparations. Immunohistochemistry: Suitable for frozen sections, not recommended for paraffin sections.

Application Summary :

ICC, IHC (FS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage