MRP1 (human) monoclonal antibody (MRPm6) | Enzo Life Sciences ALX-801-013-C500 product information

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MRP1 (human) monoclonal antibody (MRPm6)

catalog :

ALX-801-013-C500

quantity :

500 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MRPm6

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

Enzo Life Sciences product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:50; loading ...; fig 2a	Roundhill E, Turnbull D, Burchill S. Localization of MRP-1 to the outer mitochondrial membrane by the chaperone protein HSP90Î². FASEB J. 2016;30:1712-23 pubmed publisher
	Kita H, Okamoto K, Kushima R, Kawauchi A, Chano T. Dimethyl sulfoxide induces chemotherapeutic resistance in the treatment of testicular embryonal carcinomas. Oncol Lett. 2015;10:661-666 pubmed
	PoÅºniak B, Pawlak A, ObmiÅ„ska Mrukowicz B. Flow cytometric assessment of P-glycoprotein and multidrug resistance-associated protein activity and expression in canine lymphoma. In Vivo. 2015;29:149-53 pubmed
	Luna Tortós C, Fedrowitz M, Loscher W. Evaluation of transport of common antiepileptic drugs by human multidrug resistance-associated proteins (MRP1, 2 and 5) that are overexpressed in pharmacoresistant epilepsy. Neuropharmacology. 2010;58:1019-32 pubmed publisher
	Honscha K, Schirmer A, Reischauer A, Schoon H, Einspanier A, Gabel G. Expression of ABC-transport proteins in canine mammary cancer: consequences for chemotherapy. Reprod Domest Anim. 2009;44 Suppl 2:218-23 pubmed publisher
	Perrotton T, Trompier D, Chang X, Di Pietro A, Baubichon Cortay H. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007;282:31542-8 pubmed
	Rosati A, Decorti G, Klugmann F, Candussio L, Granzotto M, Melato M, et al. Cytofluorimetric analysis of a renal tubular cell line and its resistant counterpart. Anticancer Res. 2000;20:3403-10 pubmed
	Daoud R, Kast C, Gros P, Georges E. Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1). Biochemistry. 2000;39:15344-52 pubmed
	Scheffer G, Kool M, Heijn M, de Haas M, Pijnenborg A, Wijnholds J, et al. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res. 2000;60:5269-77 pubmed
	Poulain S, Lepelley P, Preudhomme C, Cambier N, Cornillon J, Wattel E, et al. Expression of the multidrug resistance-associated protein in myelodysplastic syndromes. Br J Haematol. 2000;110:591-8 pubmed
	Daoud R, Desneves J, Deady L, Tilley L, Scheper R, Gros P, et al. The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites. Biochemistry. 2000;39:6094-102 pubmed
	Meijer G, Schroeijers A, Flens M, Meuwissen S, van der Valk P, Baak J, et al. Increased expression of multidrug resistance related proteins Pgp, MRP1, and LRP/MVP occurs early in colorectal carcinogenesis. J Clin Pathol. 1999;52:450-4 pubmed
	Sargent J, Williamson C, Hall A, Elgie A, Taylor C. Evidence for the involvement of the glutathione pathway in drug resistance in AML. Adv Exp Med Biol. 1999;457:205-9 pubmed
	Borg A, Burgess R, Green L, Scheper R, Yin J. Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukaemia cells predict a poor response to chemotherapy and reduced patient survival. Br J Haematol. 1998;103:1083-91 pubmed

product information

Product ID :

ALX-801-013

Catalog Number :

ALX-801-013-C500

Product Name :

MRP1 (human) monoclonal antibody (MRPm6)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

500 µg

list of Pubmed id :

20080116, 17646169, 11131640, 11112520, 11016657, 10997969, 10821682, 10562814, 10500795, 9886324

Clone :

MRPm6

Isotype :

IgG1

SPECIES REACTIVITY :

Human

ALTnames :

Multidrug resistance-associated protein 1, ABCC1

Immunogen :

Recombinant human MRP1 (multidrug resistance-associated protein 1) (aa 1294-1531).

Specificity :

Recognizes the internal epitope (P1511SDLLQQRGL1520) of human MRP1.

Buffer :

Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.

Uses :

Flow Cytometry: cell permeabilization required. Immunocytochemistry: cytospin preparations. Immunohistochemistry: Suitable for frozen sections, weak in paraffin sections.

Application Summary :

FC, ICC, IHC (FS), WB

Storage :

-20°C

more info or order :

Enzo Life Sciences product webpage