MRP1 (human) monoclonal antibody (MRPm5) | Enzo Life Sciences ALX-801-012-C250 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MRP1 (human) monoclonal antibody (MRPm5)

catalog :

ALX-801-012-C250

quantity :

250 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MRPm5

The same clone is also sold as:

Abcam: ab24102

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

citations: 9

Reference
Westlake C, Payen L, Gao M, Cole S, Deeley R. Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region. J Biol Chem. 2004;279:53571-83 pubmed
Scheffer G, Kool M, Heijn M, de Haas M, Pijnenborg A, Wijnholds J, et al. Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. Cancer Res. 2000;60:5269-77 pubmed
den Boer M, Zwaan C, Pieters R, Kazemier K, Rottier M, Flens M, et al. Optimal immunocytochemical and flow cytometric detection of P-gp, MRP and LRP in childhood acute lymphoblastic leukemia. Leukemia. 1997;11:1078-85 pubmed
Nooter K, Bosman F, Burger H, van Wingerden K, Flens M, Scheper R, et al. Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer. Ann Oncol. 1996;7:75-81 pubmed
Flens M, Zaman G, van der Valk P, Izquierdo M, Schroeijers A, Scheffer G, et al. Tissue distribution of the multidrug resistance protein. Am J Pathol. 1996;148:1237-47 pubmed
Zaman G, Flens M, van Leusden M, de Haas M, Mülder H, Lankelma J, et al. The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump. Proc Natl Acad Sci U S A. 1994;91:8822-6 pubmed
Flens M, Izquierdo M, Scheffer G, Fritz J, Meijer C, Scheper R, et al. Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies. Cancer Res. 1994;54:4557-63 pubmed
Schadendorf D, Makki A, Stahr C, van Dyck A, Wanner R, Scheffer G, et al. Membrane transport proteins associated with drug resistance expressed in human melanoma. Am J Pathol. 1995;147:1545-52 pubmed
Cole S, Bhardwaj G, Gerlach J, Mackie J, Grant C, Almquist K, et al. Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science. 1992;258:1650-4 pubmed

product information

Product ID :

ALX-801-012

Catalog Number :

ALX-801-012-C250

Product Name :

MRP1 (human) monoclonal antibody (MRPm5)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

250 µg

list of Pubmed id :

15459206, 11016657, 9204995, 9081396, 8644864, 7916458, 7914828, 7495278, 1360704

Clone :

MRPm5

Isotype :

IgG2

SPECIES REACTIVITY :

Human

ALTnames :

Multidrug resistance-associated protein 1, ABCC1

Immunogen :

Recombinant human MRP1 (multidrug resistance-associated protein 1) (aa 986-1204).

Specificity :

Recognizes an internal epitope of human MRP1, overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

Buffer :

Liquid. In serum free culture supernatant containing 0.7% BSA and 0.1% sodium azide.

Uses :

Flow Cytometry: cell permeabilization required. Immunocytochemistry: cytospin preparations. Immunohistochemistry: Suitable for frozen sections, weak in paraffin sections.

Application Summary :

FC, ICC, IHC (FS), WB

Storage :

-20°C