MRP1 (human) monoclonal antibody (QCRL-1) | Enzo Life Sciences ALX-801-010-L001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

antibody

product name :

MRP1 (human) monoclonal antibody (QCRL-1)

catalog :

ALX-801-010-L001

quantity :

1 ml

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

QCRL-1

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 12

Reference
Suzuki T, Ishibashi K, Yumoto A, Nishio K, Ogasawara Y. Utilization of arsenic trioxide as a treatment of cisplatin-resistant non-small cell lung cancer PC-9/CDDP and PC-14/CDDP cells. Oncol Lett. 2015;10:805-809 pubmed
Qin L, Tam S, Deeley R. Effect of multiple cysteine substitutions on the functionality of human multidrug resistance protein 1 expressed in human embryonic kidney 293 cells: identification of residues essential for function. Drug Metab Dispos. 2012;40:1403-13 pubmed publisher
Daoud R, Kast C, Gros P, Georges E. Rhodamine 123 binds to multiple sites in the multidrug resistance protein (MRP1). Biochemistry. 2000;39:15344-52 pubmed
Daoud R, Desneves J, Deady L, Tilley L, Scheper R, Gros P, et al. The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites. Biochemistry. 2000;39:6094-102 pubmed
Filipits M, Malayeri R, Suchomel R, Pohl G, Stranzl T, Dekan G, et al. Expression of the multidrug resistance protein (MRP1) in breast cancer. Anticancer Res. 1999;19:5043-9 pubmed
Mao Q, Leslie E, Deeley R, Cole S. ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells. Biochim Biophys Acta. 1999;1461:69-82 pubmed
Filipits M, Stranzl T, Pohl G, Suchomel R, Zöchbauer S, Brunner R, et al. MRP expression in acute myeloid leukemia. An update. Adv Exp Med Biol. 1999;457:141-50 pubmed
Rao V, Dahlheimer J, Bardgett M, Snyder A, Finch R, Sartorelli A, et al. Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug-permeability barrier. Proc Natl Acad Sci U S A. 1999;96:3900-5 pubmed
Hipfner D, Gao M, Scheffer G, Scheper R, Deeley R, Cole S. Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP). Br J Cancer. 1998;78:1134-40 pubmed
Filipits M, Suchomel R, Dekan G, Haider K, Valdimarsson G, Depisch D, et al. MRP and MDR1 gene expression in primary breast carcinomas. Clin Cancer Res. 1996;2:1231-7 pubmed
Wright S, Boag A, Valdimarsson G, Hipfner D, Campling B, Cole S, et al. Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung. Clin Cancer Res. 1998;4:2279-89 pubmed
Hipfner D, Almquist K, Stride B, Deeley R, Cole S. Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1. Cancer Res. 1996;56:3307-14 pubmed

product information

Product ID :

ALX-801-010

Catalog Number :

ALX-801-010-L001

Product Name :

MRP1 (human) monoclonal antibody (QCRL-1)

Host species :

Mouse

Clonality :

Monoclonal

Product Type :

Antibody

Size :

1 ml

list of Pubmed id :

11112520, 10821682, 10697508, 10556489, 10500789, 10097135, 9820168, 9816292, 9748150, 8764126

Clone :

QCRL-1

Isotype :

IgG1

SPECIES REACTIVITY :

Human

ALTnames :

Multidrug resistance-associated protein 1, ABCC1

Immunogen :

Membranes prepared from the human small cell lung cancer cell line H69AR.

Specificity :

Recognizes the linear internal epitope (S918SYSGDI924) of human MRP1 (multidrug resistance-associated protein 1), overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

Buffer :

Liquid. 0.22μm-filtered solution in PBS containing 0.7% BSA and 0.1% sodium azide.

Uses :

Flow Cytometry: cell permeabilization required. Immunocytochemistry: cytospin preparations

Application Summary :

FC, ICC, IHC (PS), IP, WB

Storage :

-20°C