Ryanodine (high purity) | Enzo Life Sciences ALX-630-062-M005 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

Ryanodine (high purity)

catalog :

ALX-630-062-M005

quantity :

5 mg

citations: 10

Reference
Xin W, Soder R, Cheng Q, Rovner E, Petkov G. Selective inhibition of phosphodiesterase 1 relaxes urinary bladder smooth muscle: role for ryanodine receptor-mediated BK channel activation. Am J Physiol Cell Physiol. 2012;303:C1079-89 pubmed publisher
Adasme T, Haeger P, Paula Lima A, Espinoza I, Casas Alarcón M, Carrasco M, et al. Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proc Natl Acad Sci U S A. 2011;108:3029-34 pubmed publisher
Williams A, Tanna B. The interaction of ryanoids with individual ryanodine receptor channels. Biol Res. 2004;37:527-38 pubmed
Sutko J, Airey J, Welch W, Ruest L. The pharmacology of ryanodine and related compounds. Pharmacol Rev. 1997;49:53-98 pubmed
McPherson P, Campbell K. The ryanodine receptor/Ca2+ release channel. J Biol Chem. 1993;268:13765-8 pubmed
Galione A. Cyclic ADP-ribose: a new way to control calcium. Science. 1993;259:325-6 pubmed
Sutko J, Kenyon J. Ryanodine modification of cardiac muscle responses to potassium-free solutions. Evidence for inhibition of sarcoplasmic reticulum calcium release. J Gen Physiol. 1983;82:385-404 pubmed
Jenden D, Fairhurst A. The pharmacology of ryanodine. Pharmacol Rev. 1969;21:1-25 pubmed
Pessah I, Waterhouse A, Casida J. The calcium-ryanodine receptor complex of skeletal and cardiac muscle. Biochem Biophys Res Commun. 1985;128:449-56 pubmed
Feher J, Lipford G. Mechanism of action of ryanodine on cardiac sarcoplasmic reticulum. Biochim Biophys Acta. 1985;813:77-86 pubmed

product information

Product ID :

ALX-630-062

Catalog Number :

ALX-630-062-M005

Product Name :

Ryanodine (high purity)

Product Type :

Biochemical

Size :

5 mg

list of Pubmed id :

22992675, 21282625, 15709679, 9085309, 8390976, 8380506, 6631403, 4887724, 3985981, 3155965

Product Description :

Induces the release of intracellular Ca2+ . Ryanodine receptors mediate adenine nucleotide, Ca2+ and caffeine-sensitive release of Ca2+ from sarcoplasmic reticulum of cardiac and skeletal muscle and may also mediate intracellular Ca2+ release in neurons. Biphasic effect on sarcoplasmic reticulum calcium channels; Nanomolar levels open the channel and micromolar levels close it.

Purity :

≥99% (HPLC)

Storage :

-20°C