This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
chemical
product name :
AIDA
catalog :
ALX-550-101-M025
quantity :
25 mg
citations: 9
Reference
Pellegrini Giampietro D, Cozzi A, Peruginelli F, Leonardi P, Meli E, Pellicciari R, et al. 1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia. Eur J Neurosci. 1999;11:3637-47 pubmed
Camodeca N, Breakwell N, Rowan M, Anwyl R. Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro. Neuropharmacology. 1999;38:1597-606 pubmed
Salt T, Turner J, Kingston A. Evaluation of agonists and antagonists acting at Group I metabotropic glutamate receptors in the thalamus in vivo. Neuropharmacology. 1999;38:1505-10 pubmed
Schoepp D, Jane D, Monn J. Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology. 1999;38:1431-76 pubmed
Pellicciari R, Costantino G. Metabotropic G-protein-coupled glutamate receptors as therapeutic targets. Curr Opin Chem Biol. 1999;3:433-40 pubmed
Mukhin A, Ivanova S, Faden A. mGluR modulation of post-traumatic neuronal death: role of NMDA receptors. Neuroreport. 1997;8:2561-6 pubmed
Nielsen K, Macphail E, Riedel G. Class I mGlu receptor antagonist 1-aminoindan-1,5-dicarboxylic acid blocks contextual but not cue conditioning in rats. Eur J Pharmacol. 1997;326:105-8 pubmed
Moroni F, Lombardi G, Thomsen C, Leonardi P, Attucci S, Peruginelli F, et al. Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent mGluR1 antagonist. J Pharmacol Exp Ther. 1997;281:721-9 pubmed
Pellicciari R, Luneia R, Costantino G, Marinozzi M, Natalini B, Jakobsen P, et al. 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. J Med Chem. 1995;38:3717-9 pubmed
product information
Product ID :
ALX-550-101
Catalog Number :
ALX-550-101-M025
Product Name :
AIDA
Product Type :
Biochemical
Size :
25 mg
list of Pubmed id :
10564371, 10530821, 10530812, 10530808, 10419848, 9261827, 9196260, 9152378, 7562903
Product Description :
Potent and selective ligand for group I mGluRs. Shows no effect on group II or group III mGluRs. Has no effect on ionotropic glutamate receptors.
ALTnames :
(±)-1-Aminoindane-1,5-dicarboxylic acid, UPF 523
Purity :
≥96%
Storage :
+4°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.