NBQX | Enzo Life Sciences ALX-550-044-M025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

chemical

product name :

NBQX

catalog :

ALX-550-044-M025

quantity :

25 mg

citations: 10

Reference
Koroshetz W, Moskowitz M. Emerging treatments for stroke in humans. Trends Pharmacol Sci. 1996;17:227-33 pubmed
Bernert H, Turski L. Traumatic brain damage prevented by the non-N-methyl-D-aspartate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo[f] quinoxaline. Proc Natl Acad Sci U S A. 1996;93:5235-40 pubmed
Namba T, Morimoto K, Sato K, Yamada N, Kuroda S. Antiepileptogenic and anticonvulsant effects of NBQX, a selective AMPA receptor antagonist, in the rat kindling model of epilepsy. Brain Res. 1994;638:36-44 pubmed
Pook P, Brugger F, Hawkins N, Clark K, Watkins J, Evans R. A comparison of the actions of agonists and antagonists at non-NMDA receptors of C fibres and motoneurones of the immature rat spinal cord in vitro. Br J Pharmacol. 1993;108:179-84 pubmed
Buchan A, Lesiuk H, Barnes K, Li H, Huang Z, Smith K, et al. AMPA antagonists: do they hold more promise for clinical stroke trials than NMDA antagonists?. Stroke. 1993;24:I148-52 pubmed
Sheardown M. The pharmacology of AMPA receptors and their antagonists. Stroke. 1993;24:I146-7; discussion I153-4 pubmed
Muller D, Joly M, Lynch G. Contributions of quisqualate and NMDA receptors to the induction and expression of LTP. Science. 1988;242:1694-7 pubmed
Sheardown M, Nielsen E, Hansen A, Jacobsen P, Honore T. 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science. 1990;247:571-4 pubmed
Gill R, Nordholm L, Lodge D. The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model. Brain Res. 1992;580:35-43 pubmed
Randle J, Guet T, Cordi A, Lepagnol J. Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitution. Eur J Pharmacol. 1992;215:237-44 pubmed

product information

Product ID :

ALX-550-044

Catalog Number :

ALX-550-044-M025

Product Name :

NBQX

Product Type :

Biochemical

Size :

25 mg

list of Pubmed id :

8763201, 8643559, 8199874, 8094024, 7504338, 7504337, 2904701, 2154034, 1504814, 1382998

Product Description :

Most potent and selective AMPA/kainate receptor antagonist. For the more soluble form see NBQX . disodium salt (Prod. No. ALX-550-272).

ALTnames :

2,3-Dihydroxy-6-nitro-7-sulphamoylbenzo(f)-quinoxaline, 6-Nitro-7-sulphamoylbenzo(f)-quinoxaline-2,3-dione

Purity :

≥99% (HPLC)

Storage :

+4°C