IL-33 (human), (recombinant) | Enzo Life Sciences ALX-522-098-3010 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

IL-33 (human), (recombinant)

catalog :

ALX-522-098-3010

quantity :

3 x 10 µg

citations: 2

Reference
Pecaric Petkovic T, Didichenko S, Kaempfer S, Spiegl N, Dahinden C. Human basophils and eosinophils are the direct target leukocytes of the novel IL-1 family member IL-33. Blood. 2009;113:1526-34 pubmed publisher
Carriere V, Roussel L, Ortega N, Lacorre D, Americh L, Aguilar L, et al. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci U S A. 2007;104:282-7 pubmed

product information

Product ID :

ALX-522-098

Catalog Number :

ALX-522-098-3010

Product Name :

IL-33 (human), (recombinant)

Product Type :

Protein

Size :

3 x 10 µg

list of Pubmed id :

18955562, 17185418

Background :

IL-33 is a member of the IL-1 family. It is involved in T helper type 2 response via the activation of its receptor ST2 (IL-1RL1) driving the production of Th2-associated cytokines. The stimulation of ST2 by IL-33 induces the NF-κB and MAPK pathways. The human IL-33 protein is expressed with a prodomain (aa 1-111) which is cleaved by caspase-1 to produce the 18kDa mature protein (112-270). Historical data has shown that IL-33 activates human ST2-dependent NF-κB pathway, but it does not activate mouse ST2-dependent NF-κB.

ALTnames :

Interleukin-33, NF-HEV, IL-1F11

Specificity :

Binds to human ST2.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Storage :

-20°C