This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
Profilin (Toxoplasma gondii), (recombinant) (GST-tag)
catalog :
ALX-522-093-C010
quantity :
10 µg
product information
Product ID :
ALX-522-093
Catalog Number :
ALX-522-093-C010
Product Name :
Profilin (Toxoplasma gondii), (recombinant) (GST-tag)
Product Type :
Protein
Size :
10 µg
Background :
The initial recognition of pathogens during host defense is mediated by a family of receptors termed toll-like receptors (TLR). TLRs recognize conserved microbial components, termed pathogen-associated molecular patterns (PAMPs). To date, 11 TLRs have been cloned in mammals and each receptor appears to be involved in the recognition of a unique set of PAMPs that are distinct in their chemical nature and structure. TLR11 has a role in uropathogenic E. coli infection and senses the profilin protein from the protozoan parasite Toxoplasma gondii. Profilins are a class of small actin-binding proteins present only in eukaryotic cells. T. gondii profilin shares significant homology only with profilin genes from other apicomplexan protozoa, such as the malaria parasite, Plasmodium falciparum, suggesting that TLR11 may be involved in the recognition of these parasites. Profilin activates and induces TLR11-dependent IL-12p40 production from dendritic cells, and is known to bind TLR11 from mouse.
ALTnames :
Inflammatory profilin, Toll-like receptor 11 ligand, TLR11 ligand
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.