This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
Fn14 (human):Fc (human), (recombinant)
catalog :
ALX-522-086-C050
quantity :
50 µg
citations: 1
Reference
De A, Park J, Kawamura K, Chen R, Klein C, Rauch R, et al. Intraovarian tumor necrosis factor-related weak inducer of apoptosis/fibroblast growth factor-inducible-14 ligand-receptor system limits ovarian preovulatory follicles from excessive luteinization. Mol Endocrinol. 2006;20:2528-38 pubmed
product information
Product ID :
ALX-522-086
Catalog Number :
ALX-522-086-C050
Product Name :
Fn14 (human):Fc (human), (recombinant)
Product Type :
Protein
Size :
50 µg
list of Pubmed id :
16762976
SPECIES REACTIVITY :
Human, Mouse
Background :
The fibroblast growth factor-inducible-14 (Fn14) is a 129 aa type Ia transmembrane protein. Fn14 is a growth-factor regulated, immediate-early response protein. It is expressed in a developmental and adult tissue-specific manner. Fn14 expression decreases cellular adhesion to extracellular matrix proteins fibronectin and vitronectin and reduces cell growth and migration. It is expressed at high levels in liver cancer cells, in hepatocellular carcinoma specimens as well as in regenerating liver cells showing Fn14 may play a role in hepatocyte growth and liver neoplasia. Fn14 binds to TWEAK (Apo-3 Ligand), a member of the TNF family. Historical data has shown that Fn14 inhibits TWEAK-mediated killing of Kym-1 target cells.
ALTnames :
Fibroblast growth factor-inducible immediate-early response protein 14, TNFRSF 12A, TWEAK-R, CD266
Specificity :
Binds human and mouse TWEAK.
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Uses :
ELISA: binds to TWEAK at 1-10 ng/ml.
Application Summary :
ELISA
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.