BAFF-R (mouse):Fc (human), (recombinant) | Enzo Life Sciences ALX-522-080-C050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Enzo Life Sciences

other brands :

Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis

product type :

protein

product name :

BAFF-R (mouse):Fc (human), (recombinant)

catalog :

ALX-522-080-C050

quantity :

50 µg

citations: 1

Reference
Huard B, Arlettaz L, Ambrose C, Kindler V, Mauri D, Roosnek E, et al. BAFF production by antigen-presenting cells provides T cell co-stimulation. Int Immunol. 2004;16:467-75 pubmed

product information

Product ID :

ALX-522-080

Catalog Number :

ALX-522-080-C050

Product Name :

BAFF-R (mouse):Fc (human), (recombinant)

Product Type :

Protein

Size :

50 µg

list of Pubmed id :

14978020

Background :

BAFF-R:Fc is 10-fold more efficacious than BCMA:Fc for blocking BAFF-induced B cell proliferation in vitro and for blocking BAFF-mediated survival of mouse splenic B lymphocytes in vivo. Thus BAFF-R:Fc becomes a promising therapeutic candidate as a BAFF-neutralizing compound in autoimmune disease intervention. Historical data has shown that BAFF-R blocks the binding of mouse and human BAFF to their BAFF-receptors, inhibiting BAFF-mediated splenocyte survival.

ALTnames :

TNFRSF 13C, BR3, BlySR3, CD268

Specificity :

Binds mouse and human BAFF.

Purity :

≥95% (SDS-PAGE)

Buffer :

Lyophilized. Contains PBS.

Uses :

ELISA: binds to BAFF. Flow Cytometry: Detection of membrane-bound mouse and human BAFF in combination with fluorescently labelled Ab to IgG1.

Application Summary :

ELISA, FC, FUNC

Storage :

-20°C