This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
DR3 (human):Fc (human), (recombinant)
catalog :
ALX-522-040-C050
quantity :
50 µg
product information
Product ID :
ALX-522-040
Catalog Number :
ALX-522-040-C050
Product Name :
DR3 (human):Fc (human), (recombinant)
Product Type :
Protein
Size :
50 µg
Background :
The DR3 receptor (WSL-1, Apo-3, LARD, TRAMP, TR3) is a member of the tumor necrosis factor receptor (TNF-R) family. DR3 is a type I transmembrane receptor. It is 339 aa long and contains 4 extracellular cysteine-rich motifs in its extracellular domain, while its cytoplasmic region contains a death domain. DR3 is abundantly expressed on thymocytes and T and B lymphocytes. Overexpression of DR3 mediates activation of nuclear factor NF-κB and induces apoptosis. Besides the induction of apoptosis, DR3 has been reported to regulate negative selection during thymocyte development.
ALTnames :
WSL-1, Apo-3, LARD, TRAMP, TR3, TNFRSF 12, TNFRSF 25, Death receptor 3
Specificity :
Binds human TL1A.
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Uses :
Can be used together with anti-human IgG1 PAb to detect TL1A.
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.