This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Enzo Life Sciences
other brands :
Stressgen, BioMol, Alexis Corporation, Assay Designs, Alexis
product type :
protein
product name :
RANK (human):Fc (human), (recombinant)
catalog :
ALX-522-039-C050
quantity :
50 µg
product information
Product ID :
ALX-522-039
Catalog Number :
ALX-522-039-C050
Product Name :
RANK (human):Fc (human), (recombinant)
Product Type :
Protein
Size :
50 µg
SPECIES REACTIVITY :
Human, Mouse
Background :
The receptor activator of NF-κB (RANK) is a member of the tumor necrosis factor receptor (TNF-R) family. RANK is a type I transmembrane receptor. It is 616 aa long and contains 4 cysteine-rich motifs in its extracellular domain, while its long cytoplasmic domain spans 383 aa. RANK is mainly expressed on dendritic cells. After binding its ligand RANKL, RANK interacts with TNF receptor-associated factor 1 (TRAF1), TRAF2, TRAF3, TRAF5 and TRAF6 which mediate activation of nuclear factor NF-κB and JNK. RANK-RANKL interactions promote survival of dendritic cells as well as differentiation in osteoclasts. Historical data has shown that RANK inhibits human rhsRANKL-induced survival of dendritic cells and osteoclasts.
ALTnames :
TRANCE-R, TNFRSF 11A, ODFR, CD265
Specificity :
Binds human and mouse RANKL.
Purity :
≥95% (SDS-PAGE)
Buffer :
Lyophilized. Contains PBS.
Uses :
ELISA: binds to RANKL.
Application Summary :
ELISA
Storage :
-20°C
company information
Enzo Life Sciences
5777 Hines Drive
Ann Arbor, MI 48108
info-us@enzolifesciences.
https://www.enzolifesciences.com
1-800-942-0430
headquarters: USA
Enzo Life Sciences, incorporating ALEXIS® Biochemicals and BIOMOL® International, offers a comprehensive panel of innovative life science reagents. Antibodies, enzymes, proteins, small molecule inhibitors, product libraries, and assay kits are available for research in Cancer, Cell Death, Epigenetics, Genomics, Immunology, Neuroscience, Signal Transduction, and Ubiquitin & Proteasomes, Enabling Discovery in Life Science(tm). Visit www.enzolifesciences.com.